In situ reactions of metal ions or their compounds are important mechanisms by which
particles alter lung immune responses. The authors hypothesized that major determinants of …

Increasing the understanding of how metal ions/complexes react in situ will allow for the
improved specificity and controlled toxicity of novel synthetic metallocompounds that will be …

The in situ reactions of metal ions/complexes are important in understanding the
mechanisms by which environmental and occupational metal particles alter lung immune …

Transition metals are components of airborne particles and have been implicated in adverse
health effects. The relative inflammatory potential of these metals is usually inferred from …

Epidemiologic studies demonstrate that infection, specifically pneumonia, contributes
substantially to the increased morbidity and mortality among elderly individuals following …

Nutritional immunity is the sequestration of bioavailable trace metals such as iron, zinc and
copper by the host to limit pathogenicity by invading microorganisms. As one of the most …

It was hypothesized that relative mass relationships among select constituent metals and
iron (Fe3+) govern the pulmonary immunotoxic potential of any PM2. 5 sample, as these …

Mechanisms for pathogenic metal signaling in airway injury or disease promotion are poorly
understood. It is widely believed that one mechanism for pathogenic and possible …

The field of immunotoxicology had its inception in the early 1970s; the science of pulmonary
toxicology has been recognized for more than forty years. With increasing research efforts in …

The lung presents a unique challenge for iron homeostasis. The entire airway is in direct
contact with the environment and its iron particulate matter and iron-utilizing microbes …