The role of complement in cancer has received increasing attention over the last decade.
Recent studies provide compelling evidence that complement accelerates cancer …

Constituent of innate immunity, complement is present in the tumor microenvironment. The
functions of complement include clearance of pathogens and maintenance of homeostasis …

Complement is a central part of the immune system that has developed as a first defense
against non-self cells. Neoplastic transformation is accompanied by an increased capacity of …

Despite significant research on the role of inflammation and immunosurveillance in the
immunologic microenvironment of tumors, little attention has been given to the oncogenic …

Simple Summary Increasing evidence supports a role for complement in the development of
cancer and the response to cancer treatments. Dysregulated complement expression within …

Complement is an effector of innate immunity and a bridge connecting innate immunity and
subsequent adaptive immune responses. It is essential for protection against infections and …

For decades, complement has been recognized as an effector arm of the immune system
that contributes to the destruction of tumor cells. In fact, many therapeutic strategies have …

The complement system has traditionally been considered a component of innate immunity
against invading pathogens and “nonself” cells. Recent studies have demonstrated the …

For decades, complement has been recognized as an effector arm of the immune system
that contributes to the destruction of tumor cells. In fact, many therapeutic strategies have …

The tumour microenvironment (TME) highly influences the growth and spread of tumours,
thus impacting the patient's clinical outcome. In this context, the complement system plays a …