Production of chondroitin sulfate and chondroitin

C Schiraldi, D Cimini, M De Rosa - Applied microbiology and …, 2010 - Springer
The production of microbial polysaccharides has recently gained much interest because of
their potential biotechnological applications. Several pathogenic bacteria are known to …

Chondroitin sulfate and its derivatives: A review of microbial and other production methods

AE Awofiranye, J Hudson, AD Tithi, RJ Linhardt… - Fermentation, 2022 - mdpi.com
Chondroitin sulfate (CS) is widely used across the world as a nutraceutical and
pharmaceutical. Its high demand and potential limitations in current methods of extraction …

Chondroitin sulfate: Extraction, purification, microbial and chemical synthesis

Y Shi, Y Meng, J Li, J Chen, Y Liu… - Journal of Chemical …, 2014 - Wiley Online Library
Chondroitin sulfate, a type of acid mucopolysaccharide possessing a variety of bioactivities,
has attracted tremendous interest due to its use in the relief of joint diseases. It has been …

A microbiological–chemical strategy to produce chondroitin sulfate A, C

E Bedini, C De Castro, M De Rosa, A Di Nola… - Angewandte Chemie …, 2011 - infona.pl
No pigs, no cows needed: Chondroitin sulfate for pharmacological uses is obtained from
animal sources in low abundance and with a laborious downstream purification. It has now …

Heparin and related polysaccharides: synthesis using recombinant enzymes and metabolic engineering

M Suflita, L Fu, W He, M Koffas, RJ Linhardt - Applied microbiology and …, 2015 - Springer
Glycosaminoglycans are linear anionic polysaccharides that exhibit a number of important
biological and pharmacological activities. The two most prominent members of this class of …

Biotechnological advances in the synthesis of modified chondroitin towards novel biomedical applications

D Cimini, E Bedini, C Schiraldi - Biotechnology Advances, 2023 - Elsevier
Chondroitin sulfate (CS) is a well-known glycosaminoglycan present in a large variety of
animal tissues, with an outstanding structural heterogeneity mainly related to molecular …

Advances and challenges in biotechnological production of chondroitin sulfate and its oligosaccharides

W Zhang, R Xu, J Chen, H Xiong, Y Wang… - International journal of …, 2023 - Elsevier
Chondroitin sulfate (CS) is a member of glycosaminoglycans (GAGs) and has critical
physiological functions. CS is widely applied in medical and clinical fields. Currently, the …

Glycosaminoglycan polysaccharide biosynthesis and production: today and tomorrow

PL DeAngelis - Applied Microbiology and Biotechnology, 2012 - Springer
Glycosaminoglycans [GAGs] are essential heteropolysaccharides in vertebrate tissues that
are also, in certain cases, employed as virulence factors by microbes. Hyaluronan [HA] …

Production of capsular polysaccharide from Escherichia coli K4 for biotechnological applications

D Cimini, OF Restaino, A Catapano, M De Rosa… - Applied microbiology …, 2010 - Springer
The production of industrially relevant microbial polysaccharides has recently gained much
interest. The capsular polysaccharide of Escherichia coli K4 is almost identical to …

A microbial–enzymatic strategy for producing chondroitin sulfate glycosaminoglycans

Z Zhou, Q Li, H Huang, H Wang, Y Wang… - Biotechnology and …, 2018 - Wiley Online Library
Chondroitin sulfate has been widely used in both medical and clinical applications.
Commercial chondroitin sulfate has been mainly acquired from animal tissue extraction …