High expression of Talin-1 is associated with tumor progression and recurrence in melanoma skin cancer patients

Y Rezaie, F Fattahi, B Mashinchi, K Kamyab Hesari… - BMC cancer, 2023 - Springer
Background Talin-1 as a component of multi-protein adhesion complexes plays a role in
tumor formation and migration in various malignancies. This study investigated Talin-1 in …

Promotive effect of Talin‐1 protein on gastric cancer progression through PTK2‐PXN‐VCL‐E‐Cadherin‐CAPN2‐MAPK1 signaling axis

H Yan, M Guo, J Zou, F Xiao, L Yi… - Journal of clinical …, 2020 - Wiley Online Library
Objective Our research group was aim to explore the molecular mechanism of Talin‐1
protein affecting gastric cancer progression through PTK2‐PXN‐VCL‐E‐Cadherin‐CAPN2 …

MYC upregulated LINC00319 promotes human acute myeloid leukemia (AML) cells growth through stabilizing SIRT6

Y Zhang, Z Huang, F Sheng, Z Yin - Biochemical and biophysical research …, 2019 - Elsevier
Long non-coding RNAs (lncRNAs) have been identified by accumulating studies as critical
regulator in tumorigenesis and tumor development in human cancers, including in acute …

Differential Expression of the TLR4 Gene in Pan-Cancer and Its Related Mechanism

J Hu, J Xu, X Feng, Y Li, F Hua, G Xu - Frontiers in Cell and …, 2021 - frontiersin.org
Previous studies have revealed the relationship between toll-like receptor 4 (TLR4)
polymorphisms and cancer susceptibility. However, the relationship between TLR4 and …

[HTML][HTML] Analysis of prognostic biomarker models of TXNIP/NLRP3/IL1B inflammasome pathway in patients with acute myeloid leukemia

J Chen, Q Hou, T Chang, J Zheng, C Yao… - … Journal of Medical …, 2024 - ncbi.nlm.nih.gov
Background: Exploring potential biomarkers for predicting clinical outcomes and developing
targeted therapies for acute myeloid leukemia (AML) is of utmost importance. This study …

Thymidine kinase 1 as a target is regulated by the hsa-let-7b-5p/LINC00665 axis and affects NSCLC prognosis

XD Zhu, YF Fan, Y Zhao, XY Song, XS Liu, ZJ Gao… - Heliyon, 2023 - cell.com
Background In the past, multiple studies have offered incremental evidence that indicates
that competitive endogenous RNA (ceRNA) regulatory networks are involved in tumor …

[HTML][HTML] Integration analysis using bioinformatics and experimental validation on the clinical and biological significance of TSLP in cancers

H Qu, X Liu, T Jiang, G Huang, H Cai, D Xing, Y Mao… - Cellular …, 2023 - Elsevier
Thymic stromal lymphopoietin (TSLP) has significantly impacted the development and
progression of various neoplastic disorders. To comprehensively evaluate the diverse …

TSC22D3 as an immune-related prognostic biomarker for acute myeloid leukemia

Y Li, H Huang, Z Zhu, S Chen, Y Liang, L Shu - Iscience, 2023 - cell.com
Acute myeloid leukemia (AML) is the type of hematologic neoplasm most common in adults.
Glucocorticoid-induced gene TSC22D3 regulates cell proliferation through its function as a …

Identification of potential novel prognosis-related genes through transcriptome sequencing, bioinformatics analysis, and clinical validation in acute myeloid leukemia

J Wang, MN Uddin, J Hao, R Chen, Y Xiang… - Frontiers in …, 2021 - frontiersin.org
Background: Acute Myeloid Leukemia (AML) is a complex and heterogeneous hematologic
malignancy. However, the function of prognosis-related signature genes in AML remains …

[HTML][HTML] Analyzing the key gene expression and prognostics values for acute myeloid leukemia

L Shi, Y Huang, X Huang, W Zhou, J Wei… - Translational Cancer …, 2020 - ncbi.nlm.nih.gov
Background Acute myeloid leukemia (AML) is one of the first tumor types sequenced at the
whole genome level. However, numbers of the mutated genes expression levels, functions …