Interleukin‐6 receptor inhibition with tocilizumab reduces disease activity in rheumatoid arthritis with inadequate response to disease‐modifying antirheumatic drugs …
MC Genovese, JD McKay, EL Nasonov… - … : Official Journal of …, 2008 - Wiley Online Library
Objective To examine the efficacy and safety of the humanized anti–interleukin‐6 receptor
antibody tocilizumab combined with conventional disease‐modifying antirheumatic drugs …
antibody tocilizumab combined with conventional disease‐modifying antirheumatic drugs …
Interleukin‐6 receptor inhibition with tocilizumab and attainment of disease remission in rheumatoid arthritis: the role of acute‐phase reactants
JS Smolen, D Aletaha - Arthritis & Rheumatism, 2011 - Wiley Online Library
Objective To determine the effects of tocilizumab on rheumatoid arthritis (RA) disease
activity and remission assessment, using measures that do or do not comprise acute‐phase …
activity and remission assessment, using measures that do or do not comprise acute‐phase …
Effectiveness and safety of the interleukin 6-receptor antagonist tocilizumab after 4 and 24 weeks in patients with active rheumatoid arthritis: the first phase IIIb real-life …
Objectives To confirm the effectiveness and safety of the interleukin 6-receptor antagonist
tocilizumab in patients with rheumatoid arthritis (RA) in a setting close to real-life medical …
tocilizumab in patients with rheumatoid arthritis (RA) in a setting close to real-life medical …
Double‐blind randomized controlled clinical trial of the interleukin‐6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an …
RN Maini, PC Taylor, J Szechinski… - Arthritis & …, 2006 - Wiley Online Library
Objective To establish the safety and efficacy of repeat infusions of tocilizumab (previously
known as MRA), a humanized anti–interleukin‐6 (IL‐6) receptor antibody, alone and in …
known as MRA), a humanized anti–interleukin‐6 (IL‐6) receptor antibody, alone and in …
Study of active controlled tocilizumab monotherapy for rheumatoid arthritis patients with an inadequate response to methotrexate (SATORI): significant reduction in …
N Nishimoto, N Miyasaka, K Yamamoto… - Modern …, 2009 - academic.oup.com
We investigated the clinical efficacy and safety of tocilizumab (a humanized anti-IL-6
receptor antibody) monotherapy in active rheumatoid arthritis (RA) patients with an …
receptor antibody) monotherapy in active rheumatoid arthritis (RA) patients with an …
Comparison of tocilizumab monotherapy versus methotrexate monotherapy in patients with moderate to severe rheumatoid arthritis: the AMBITION study
G Jones, A Sebba, J Gu, MB Lowenstein… - Annals of the …, 2010 - ard.bmj.com
Background: The anti-interleukin (IL) 6 receptor antibody tocilizumab inhibits signalling of
IL6, a key cytokine in rheumatoid arthritis (RA) pathogenesis. Objective: To evaluate through …
IL6, a key cytokine in rheumatoid arthritis (RA) pathogenesis. Objective: To evaluate through …
Long-term safety and efficacy of tocilizumab, an anti-IL-6 receptor monoclonal antibody, in monotherapy, in patients with rheumatoid arthritis (the STREAM study) …
N Nishimoto, N Miyasaka, K Yamamoto… - Annals of the …, 2009 - ard.bmj.com
Objectives: To evaluate the safety and efficacy of 5-year, long-term tocilizumab monotherapy
for patients with rheumatoid arthritis. Methods: In an open-label, long-term extension trial …
for patients with rheumatoid arthritis. Methods: In an open-label, long-term extension trial …
Efficacy of tocilizumab in patients with moderate to severe active rheumatoid arthritis and a previous inadequate response to disease-modifying antirheumatic drugs …
Y Yazici, JR Curtis, A Ince, H Baraf… - Annals of the …, 2012 - ard.bmj.com
Objective To evaluate efficacy of tocilizumab in US patients with moderate to severe active
rheumatoid arthritis (RA) and inadequate clinical response to disease-modifying …
rheumatoid arthritis (RA) and inadequate clinical response to disease-modifying …
Indirect comparison of tocilizumab and other biologic agents in patients with rheumatoid arthritis and inadequate response to disease-modifying antirheumatic drugs
GJD Bergman, MC Hochberg, M Boers… - Seminars in arthritis and …, 2010 - Elsevier
OBJECTIVES: To compare the patterns of American College of Rheumatology (ACR)
response between tocilizumab and other biologic agents in patients with rheumatoid arthritis …
response between tocilizumab and other biologic agents in patients with rheumatoid arthritis …
IL-6 receptor inhibition with tocilizumab improves treatment outcomes in patients with rheumatoid arthritis refractory to anti-tumour necrosis factor biologicals: results …
P Emery, E Keystone, HP Tony, A Cantagrel… - Annals of the …, 2008 - ard.bmj.com
Objectives: The phase III RADIATE study examined the efficacy and safety of tocilizumab, an
anti-IL-6 receptor monoclonal antibody in patients with rheumatoid arthritis (RA) refractory to …
anti-IL-6 receptor monoclonal antibody in patients with rheumatoid arthritis (RA) refractory to …
相关搜索
- inadequate response antirheumatic drugs
- inadequate response rheumatoid arthritis
- antirheumatic drugs rheumatoid arthritis
- receptor inhibition rheumatoid arthritis
- antirheumatic drugs tocilizumab in patients
- receptor inhibition tocilizumab in patients
- disease remission rheumatoid arthritis
- previous inadequate response
- tocilizumab in patients rheumatoid arthritis
- inadequate response indirect comparison
- antirheumatic drugs indirect comparison
- indirect comparison rheumatoid arthritis
- receptor inhibition disease remission
- incomplete response receptor antagonist
- incomplete response european patients
- antirheumatic drugs efficacy of tocilizumab