Patient-specific hemodynamic studies have attracted considerable attention in recent years
due to their potential to improve diagnosis and optimize clinical treatment of cardiovascular …

In vitro cardiovascular device performance evaluation in a mock circulation loop (MCL) is a
necessary step prior to in vivo testing. A MCL that accurately represents the physiology of …

Heart disease is attributed as the highest cause of death in the world. Although this could be
alleviated by heart transplantation, there is a chronic shortage of donor hearts and so …

Abstract Purpose Mock circulatory loops (MCLs) can reproducibly generate physiologically
relevant pressures and flows for cardiovascular device testing. These systems have been …

Goal: This work presents the development of a Hybrid Mock Circulatory Loop (HMCL) to
simulate hemodynamics at patient-specific level in terms of both 3D geometry and …

The mock circulatory loop (MCL) is an in vitro experimental system that can provide
continuous pulsatile flows and simulate different physiological or pathological parameters of …

The aim of this study was to develop an integrated mock circulation system that functions in
a physiological manner for testing cardiovascular devices under well-controlled …

The importance of experimental setups able to reproduce cardiac functions was well
established in the field of clinical innovations. The mock circulatory loops acquired rising …

Cardiovascular assist devices are tested in mock circulation loops (MCLs) prior to animal
and clinical testing. These MCLs rely on characteristics such as pneumatic parameters to …

The human heart is responsible for maintaining constant, pulsatile blood flow in the human
body. Mock circulatory loops (MCLs) have long been used as the mechanical …