SARS-CoV-2 mutations in MHC-I-restricted epitopes evade CD8+ T cell responses
B Agerer, M Koblischke, V Gudipati… - Science …, 2021 - science.org
CD8+ T cell immunity to SARS-CoV-2 has been implicated in COVID-19 severity and virus
control. Here, we identified nonsynonymous mutations in MHC-I-restricted CD8+ T cell …
control. Here, we identified nonsynonymous mutations in MHC-I-restricted CD8+ T cell …
AZD1222/ChAdOx1 nCoV-19 vaccination induces a polyfunctional spike protein–specific TH1 response with a diverse TCR repertoire
PA Swanson, M Padilla, W Hoyland… - Science translational …, 2021 - science.org
AZD1222 (ChAdOx1 nCoV-19), a replication-deficient simian adenovirus–vectored vaccine,
has demonstrated safety, efficacy, and immunogenicity against coronavirus disease 2019 in …
has demonstrated safety, efficacy, and immunogenicity against coronavirus disease 2019 in …
Multimodal single-cell datasets characterize antigen-specific CD8+ T cells across SARS-CoV-2 vaccination and infection
The immune response to SARS-CoV-2 antigen after infection or vaccination is defined by
the durable production of antibodies and T cells. Population-based monitoring typically …
the durable production of antibodies and T cells. Population-based monitoring typically …
T cells in COVID-19—united in diversity
L Swadling, MK Maini - Nature immunology, 2020 - nature.com
T cells in COVID-19 — united in diversity | Nature Immunology Skip to main content Thank
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[HTML][HTML] Dynamic SARS-CoV-2-specific B-cell and T-cell responses following immunization with an inactivated COVID-19 vaccine
Y Chen, S Yin, X Tong, Y Tao, J Ni, J Pan, M Li… - Clinical Microbiology …, 2022 - Elsevier
Objective The dynamic adaptive immune responses elicited by the inactivated virus vaccine
CoronaVac remain elusive. Methods In a prospective cohort of 100 healthcare professionals …
CoronaVac remain elusive. Methods In a prospective cohort of 100 healthcare professionals …
Concurrent human antibody and TH1 type T-cell responses elicited by a COVID-19 RNA vaccine
U Sahin, A Muik, E Derhovanessian, I Vogler, LM Kranz… - MedRxiv, 2020 - medrxiv.org
An effective vaccine is needed to halt the spread of the SARS-CoV-2 pandemic. Recently,
we reported safety, tolerability and antibody response data from an ongoing placebo …
we reported safety, tolerability and antibody response data from an ongoing placebo …
SARS-CoV-2 T cell immunity: Specificity, function, durability, and role in protection
DM Altmann, RJ Boyton - Science immunology, 2020 - science.org
In efforts to synthesize a clear understanding of SARS-CoV-2 (severe acute respiratory
syndrome coronavirus 2) protective immunity, antibody analysis has been paralleled by T …
syndrome coronavirus 2) protective immunity, antibody analysis has been paralleled by T …
Protective heterologous T cell immunity in COVID-19 induced by the trivalent MMR and Tdap vaccine antigens
Background T cells control viral infection, promote vaccine durability, and in coronavirus
disease 2019 (COVID-19) associate with mild disease. We investigated whether prior …
disease 2019 (COVID-19) associate with mild disease. We investigated whether prior …
Epitope profiling reveals binding signatures of SARS-CoV-2 immune response in natural infection and cross-reactivity with endemic human CoVs
A major goal of current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
vaccine efforts is to elicit antibody responses that confer protection. Mapping the epitope …
vaccine efforts is to elicit antibody responses that confer protection. Mapping the epitope …
[HTML][HTML] Rapid induction of antigen-specific CD4+ T cells is associated with coordinated humoral and cellular immunity to SARS-CoV-2 mRNA vaccination
SARS-CoV-2 mRNA vaccines have shown remarkable clinical efficacy, but questions
remain about the nature and kinetics of T cell priming. We performed longitudinal antigen …
remain about the nature and kinetics of T cell priming. We performed longitudinal antigen …