SARS-CoV-2 breakthrough infection induces rapid memory and de novo T cell responses
Although the protective role of neutralizing antibodies against COVID-19 is well established,
questions remain about the relative importance of cellular immunity. Using 6 pMHC …
questions remain about the relative importance of cellular immunity. Using 6 pMHC …
Severely ill patients with COVID-19 display impaired exhaustion features in SARS-CoV-2–reactive CD8+ T cells
The molecular properties of CD8+ T cells that respond to SARS-CoV-2 infection are not fully
known. Here, we report on the single-cell transcriptomes of> 80,000 virus-reactive CD8+ T …
known. Here, we report on the single-cell transcriptomes of> 80,000 virus-reactive CD8+ T …
Development of a T cell-based immunodiagnostic system to effectively distinguish SARS-CoV-2 infection and COVID-19 vaccination status
Both SARS-CoV-2 infections and COVID-19 vaccines elicit memory T cell responses. Here,
we report the development of 2 pools of experimentally defined SARS-CoV-2 T cell epitopes …
we report the development of 2 pools of experimentally defined SARS-CoV-2 T cell epitopes …
Functional mapping of B-cell linear epitopes of SARS-CoV-2 in COVID-19 convalescent population
Pandemic SARS-CoV-2 has caused unprecedented mortalities. Vaccine is in urgent need to
stop the pandemic. Despite great progresses on SARS-CoV-2 vaccine development, the …
stop the pandemic. Despite great progresses on SARS-CoV-2 vaccine development, the …
One-year sustained cellular and humoral immunities in coronavirus disease 2019 (COVID-19) convalescents
J Zhang, H Lin, B Ye, M Zhao, J Zhan… - Clinical Infectious …, 2022 - academic.oup.com
Background The longitudinal antigen-specific immunity in COVID-19 convalescents is
crucial for long-term protection upon individual re-exposure to SARS-CoV-2, and even more …
crucial for long-term protection upon individual re-exposure to SARS-CoV-2, and even more …
SARS-CoV-2 breakthrough infection in vaccinees induces virus-specific nasal-resident CD8+ and CD4+ T cells of broad specificity
SARS-CoV-2 breakthrough infection in vaccinees induces virus-specific nasal-resident CD8+
and CD4+ T cells of broad specificity | Journal of Experimental Medicine | Rockefeller …
and CD4+ T cells of broad specificity | Journal of Experimental Medicine | Rockefeller …
Long-lasting T cell responses in BNT162b2 COVID-19 mRNA vaccinees and COVID-19 convalescent patients
A Hurme, P Jalkanen, J Heroum, O Liedes… - Frontiers in …, 2022 - frontiersin.org
The emergence of novel variants of the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) has made it more difficult to prevent the virus from spreading despite …
(SARS-CoV-2) has made it more difficult to prevent the virus from spreading despite …
CD8+ T cells specific for conserved coronavirus epitopes correlate with milder disease in patients with COVID-19
V Mallajosyula, C Ganjavi, S Chakraborty… - Science …, 2021 - science.org
A central feature of the SARS-CoV-2 pandemic is that some individuals become severely ill
or die, whereas others have only a mild disease course or are asymptomatic. Here, we …
or die, whereas others have only a mild disease course or are asymptomatic. Here, we …
Healthy donor T cell responses to common cold coronaviruses and SARS-CoV-2
BA Woldemeskel, AK Kwaa, CC Garliss… - The Journal of …, 2020 - Am Soc Clin Investig
BACKGROUND T cell responses to the common cold coronaviruses have not been well
characterized. Preexisting T cell immunity to severe acute respiratory syndrome coronavirus …
characterized. Preexisting T cell immunity to severe acute respiratory syndrome coronavirus …
Persistence of SARS-CoV-2-specific B and T cell responses in convalescent COVID-19 patients 6–8 months after the infection
Background Monitoring the adaptive immune responses during the natural course of severe
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection provides useful …
acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection provides useful …