Freshly prepared amorphous solid dispersions (ASDs) may not be in an equilibrium mixed
state, as high-temperatures and/or solvents are generally used during their preparation. In …

The present study details the development of a small-scale spray-drying approach for the
routine screening of amorphous solid dispersions (ASDs). This strategy aims to overcome …

Utilizing glycerol as a plasticizer, an accelerated physical stability testing method of
amorphous solid dispersions (ASDs) was developed. The influence of glycerol …

The understanding of amorphous solid dispersions has grown significantly in the past
decade. This is evident from the number of approved commercial amorphous solid …

Amorphous solid dispersions (ASD) are state-of-the art enabling formulations for poorly
water-soluble active pharmaceutical ingredients (APIs). Depending on the relative humidity …

Oral administration of drugs is preferred over other routes for several reasons: it is non-
invasive, easy to administer, and easy to store. However, drug formulation for oral …

A realistic molecular description of amorphous drug-polymer-plasticizer matrices, suitable
for the preparation of amorphous solid dispersions (ASDs) with the aid of fusion-based …

The use of amorphous solid dispersions to improve the bioavailability of active ingredients
from the BCS II and IV classifications continues to gain interest in the pharmaceutical …

Spray-dried dispersions (SDDs) have become an important formulation technology for the
pharmaceutical product development of poorly water-soluble (PWS) compounds. Although …

Amorphous solid dispersions (ASDs) are important formulation strategies for improving the
dissolution process and oral bioavailability of poorly soluble drugs. Physical stability of a …