Ginseng under forest exerts stronger anti-aging effects compared to garden ginseng probably via regulating PI3K/AKT/mTOR pathway, SIRT1/NF-κB pathway and …

M Hao, C Ding, X Peng, H Chen, L Dong, Y Zhang… - Phytomedicine, 2022 - Elsevier
Background Ginseng is deemed to be an effective anti-aging therapy. Evidence for
differences in representative active ingredients and anti-aging effects between garden …

Red ginseng has stronger anti-aging effects compared to ginseng possibly due to its regulation of oxidative stress and the gut microbiota

X Peng, M Hao, Y Zhao, Y Cai, X Chen, H Chen… - Phytomedicine, 2021 - Elsevier
Background Panax ginseng (PG) and red ginseng (RG) are considered to be effective anti-
aging treatments. However, evidence of their therapeutic mechanisms and difference in anti …

[HTML][HTML] Ginsenoside Rg1 ameliorates the cognitive deficits in D-galactose and AlCl3-induced aging mice by restoring FGF2-Akt and BDNF-TrkB signaling axis to …

SJ Zhong, L Wang, RZ Gu, WH Zhang… - International journal of …, 2020 - ncbi.nlm.nih.gov
Ginsenoside Rg1 is the main active ingredient of Panax ginseng with the activity of
neuroprotective, antioxidant and strengthening the immune system. Therefore, we …

[HTML][HTML] Korean Red Ginseng exerts anti-inflammatory and autophagy-promoting activities in aged mice

JK Kim, KK Shin, H Kim, YH Hong, W Choi… - Journal of Ginseng …, 2021 - Elsevier
Abstract Background Korean Red Ginseng (KRG) is a traditional herb that has several
beneficial properties including anti-aging, anti-inflammatory, and autophagy regulatory …

Ginsenoside Rg3 prevents cognitive impairment by improving mitochondrial dysfunction in the rat model of Alzheimer's disease

Y Zhang, X Yang, S Wang, S Song - Journal of Agricultural and …, 2019 - ACS Publications
Ginseng, the roots and rhizomes of Panax ginseng CA Meyer, is used not only as a herbal
medicine but also as a functional food to support body functions. Ginsenoside Rg3 (GRg3) is …

[HTML][HTML] Chronic dietary ginseng extract administration ameliorates antioxidant and cholinergic systems in the brains of aged mice

MR Lee, JY Ma, CK Sung - Journal of ginseng research, 2017 - Elsevier
Background Black ginseng has a more potent biological activity than non-steamed ginseng.
We investigated the effects of long-term intake of dietary black ginseng extract (BG) on …

Korean red ginseng plays an anti-aging role by modulating expression of aging-related genes and immune cell subsets

KK Shin, YS Yi, JK Kim, H Kim, MA Hossain, JH Kim… - Molecules, 2020 - mdpi.com
Despite previous reports of anti-aging effects of Korean red ginseng (KRG), the underlying
mechanisms remain poorly understood. Therefore, this study investigated possible …

[HTML][HTML] Ginseng improves cognitive deficit via the RAGE/NF-κB pathway in advanced glycation end product-induced rats

X Tan, J Gu, B Zhao, S Wang, J Yuan, C Wang… - Journal of ginseng …, 2015 - Elsevier
Background Ginseng, the root of Panax ginseng (PG), is used widely as a herbal medicine
to prevent and treat various diseases. Panax ginseng has pharmacological effects on …

Ginsenoside Rb1 retards aging process by regulating cell cycle, apoptotic pathway and metabolism of aging mice

S Yu, H Xia, Y Guo, X Qian, X Zou, H Yang… - Journal of …, 2020 - Elsevier
Abstract Ethnopharmacological relevance Ginsenoside Rb1 (GRb1), an active ingredient of
traditional Chinese medicine Panax ginseng CA Meyer, has displayed various activities …

[HTML][HTML] Administration of red ginseng ameliorates memory decline in aged mice

Y Lee, S Oh - Journal of ginseng research, 2015 - Elsevier
Background It has been known that ginseng can be applied as a potential nutraceutical for
memory impairment; however, experiments with animals of old age are few. Methods To …