Cell size varies widely among different organisms as well as within the same organism in
different tissue types and during development, which places variable metabolic and …

Cell division without growth results in progressive cell size reductions during early
embryonic development. How do the sizes of intracellular structures and organelles scale …

Organelle function is often directly related to organelle size. However, it is not necessarily
absolute size but the organelle-to-cell-size ratio that is critical. Larger cells generally have …

Among different species or cell types, or during early embryonic cell divisions that occur in
the absence of cell growth, the size of subcellular structures, including the nucleus …

Size and shape are important aspects of nuclear structure. While normal cells maintain
nuclear size within a defined range, altered nuclear size and shape are associated with a …

Just as organ size typically increases with body size, the size of intracellular structures
changes as cells grow and divide. Indeed, many organelles, such as the nucleus [1, 2] …

Cell size varies greatly among different cell types and organisms, especially during early
development when cell division is rapid with little overall growth. A fundamental question is …

Nuclear size is generally maintained within a defined range in a given cell type. Changes in
cell size that occur during cell growth, development, and differentiation are accompanied by …

Nuclear size plays pivotal roles in gene expression, embryo development, and disease. A
central hypothesis in organisms ranging from yeast to vertebrates is that nuclear size scales …

The nucleus displays a wide range of sizes and shapes in different species and cell types,
yet its size scaling and many of the key structural constituents that determine its shape are …