Purpose: This study was to investigate the effect of capecitabine on recurrent tumor and
metastasis after curative resection of liver cancer, xenograft of a highly metastatic human …

Abstract Capecitabine (N 4‐pentyloxycarbonyl‐5′‐deoxy‐5‐fluorocytidine) is a new
fluoropyrimidine carbamate, which is converted to 5‐fluorouracil (5‐FU) by 3 sequential …

Objective (s): Patient-derived xenograft (PDX) model becomes a more and more important
tool for tumor research. This study aimed to establish a colorectal cancer PDX model and …

Purpose: The aim of this study was to evaluate the combination effect of pemetrexed
disodium (MTA; Alimta; LY 231514) and gemcitabine (GEM) administered by hepatic artery …

Recurrence and metastasis are responsible for the death of non-small cell lung cancer
(NSCLC) patients. Circulating tumor cells (CTCs) in the metastatic pathway have proven to …

Purpose: We evaluated the expression of platelet-derived growth factor (PDGF) ligands and
receptors in clinical specimens of human pancreatic adenocarcinomas and determined the …

FP3 is an engineered protein which contains the extracellular domain 2 of VEGF receptor 1
(Flt-1) and extracellular domain 3 and 4 of VEGF receptor 2 (Flk-1, KDR) fused to the Fc …

Both epidermal growth factor receptor (EGF-R) signaling mechanisms and angiogenesis
have been evaluated as independent targets for therapy of human pancreatic carcinoma …

BACKGROUND Platelet‐derived endothelial cell growth factor (PD‐ECGF) is an angiogenic
factor that is expressed in various cancer tissues. Little is known regarding plasma PD …

Low-dose metronomic chemotherapy represents a new strategy to treat solid tumors by
exhibiting stronger anti-angiogenic activity and less side effects, especially in combination …