Real‐world efficacy of elbasvir and grazoprevir for hepatitis C virus (genotype 1): a nationwide, multicenter study by the Japanese Red Cross Hospital Liver Study …
T Mashiba, K Joko, M Kurosaki, H Ochi… - Hepatology …, 2019 - Wiley Online Library
Aim The present study aimed to determine the real‐world efficacy and safety of the non‐
structural protein (NS) 5A inhibitor elbasvir (EBR) combined with the NS3/4A protease …
structural protein (NS) 5A inhibitor elbasvir (EBR) combined with the NS3/4A protease …
Efficacy of 12 or 18 weeks of elbasvir plus grazoprevir with ribavirin in treatment‐naïve, noncirrhotic HCV genotype 3‐infected patients
E Gane, R Nahass, V Luketic… - Journal of viral …, 2017 - Wiley Online Library
Summary Elbasvir (EBR; HCV NS 5A inhibitor) and grazoprevir (GZR; HCV NS 3/4A
protease inhibitor) are approved as a fixed‐dose combination to treat patients chronically …
protease inhibitor) are approved as a fixed‐dose combination to treat patients chronically …
An open-label, randomized, active-controlled trial of 8 versus 12 weeks of elbasvir/grazoprevir for treatment-naive patients with chronic hepatitis C genotype 1b …
Background A 12-week grazoprevir/elbasvir regimen is highly effective against hepatitis C
virus genotype 1 (HCV-1) infection. The efficacy of an 8-week regimen for treatment-naive …
virus genotype 1 (HCV-1) infection. The efficacy of an 8-week regimen for treatment-naive …
Real-world virological efficacy and safety of elbasvir and grazoprevir in patients with chronic hepatitis C virus genotype 1 infection in Japan
H Toyoda, M Atsukawa, K Takaguchi, T Senoh… - Journal of …, 2018 - Springer
Background The real-world virological efficacy and safety of an interferon (IFN)-free direct-
acting antiviral (DAA) therapy with elbasvir (EBR) and grazoprevir (GZR) were evaluated in …
acting antiviral (DAA) therapy with elbasvir (EBR) and grazoprevir (GZR) were evaluated in …
Elbasvir/Grazoprevir for HCV infection in Russia: a randomized trial
K Zhdanov, V Isakov, E Burnevich, S Kizhlo… - Hepatic Medicine …, 2020 - Taylor & Francis
Purpose Hepatitis C virus (HCV) infection is a major healthcare concern in Russia, where
almost 5 million individuals are viremic. Elbasvir/grazoprevir is a fixed-dose combination …
almost 5 million individuals are viremic. Elbasvir/grazoprevir is a fixed-dose combination …
[PDF][PDF] Elbasvir/grazoprevir in Asia‐Pacific/Russian participants with chronic hepatitis C virus genotype 1, 4, or 6 infection
J George, E Burnevich, IS Sheen, J Heo… - Hepatology …, 2018 - Wiley Online Library
The prevalence of hepatitis C virus (HCV) infection in Asian countries is high. This study
assessed the efficacy and safety of elbasvir/grazoprevir (EBR/GZR) in participants with HCV …
assessed the efficacy and safety of elbasvir/grazoprevir (EBR/GZR) in participants with HCV …
Resistance analysis of genotype 3 hepatitis C virus indicates subtypes inherently resistant to nonstructural protein 5A inhibitors
Hepatitis C virus (HCV) genotype (gt) 3 is highly prevalent globally, with non‐gt3a subtypes
common in Southeast Asia. Resistance‐associated substitutions (RASs) have been shown …
common in Southeast Asia. Resistance‐associated substitutions (RASs) have been shown …
Effectiveness and safety of elbasvir/grazoprevir therapy in patients with chronic HCV infection: Results from the Spanish HEPA‐C real‐world cohort
M Hernández‐Conde, I Fernández… - Journal of viral …, 2019 - Wiley Online Library
In randomized controlled trials of patients with chronic HCV infection, elbasvir/grazoprevir
(EBR/GZR) demonstrated high cure rates and a good safety profile. This study assessed the …
(EBR/GZR) demonstrated high cure rates and a good safety profile. This study assessed the …
[HTML][HTML] Elbasvir/grazoprevir: a review of the latest agent in the fight against hepatitis C
AM Bell, JL Wagner, KE Barber… - International journal of …, 2016 - hindawi.com
Hepatitis C virus (HCV) is estimated to affect up to 150 million people worldwide. Despite
worldwide prevalence, treatment modalities prior to 2011 remained suboptimal, with low …
worldwide prevalence, treatment modalities prior to 2011 remained suboptimal, with low …
[HTML][HTML] Natural NS5A inhibitor resistance associated substitutions in hepatitis C virus genotype 1 infected patients from Italy
C Caudai, A Materazzi, F Saladini… - Clinical Microbiology …, 2018 - Elsevier
Objectives Genetic variability in NS5A is associated with different levels of resistance to the
currently licensed NS5A inhibitors. The aim of this study was to detect NS5A inhibitor …
currently licensed NS5A inhibitors. The aim of this study was to detect NS5A inhibitor …