Dendritic cells (DCs) are the major specialized antigen-presenting cells, thereby connecting
innate and adaptive immunity. Because of their role in establishing adaptive immunity, they …

Dendritic cells (DCs) are specialized antigen presenting cells that are central players in
inititating and directing immune responses. The phenotype and maturation state of DCs are …

Dendritic cells (DC) are key components of the immune system, which actively participate in
innate and adaptive immune responses. They are traditionally viewed as the immunologic …

Dendritic cells (DCs) are central players in immunity and are used in immune-adoptive
vaccine protocols in humans. IFN-γ, mandatory in Th-1 polarization and endowed with …

The transcription factor IRF8 is essential for the development of monocytes and dendritic
cells (DCs), whereas it inhibits neutrophilic differentiation. It is unclear how Irf8 expression is …

The mounting of an adaptive immune response is critical for removing pathogens from the
body and generating immunological memory. Central to this process are myeloid cells …

Dendritic cells (DC) develop from hematopoietic stem cells, which is guided by instructive
signals through cytokines. DC development progresses from multipotent progenitors (MPP) …

A central issue in dendritic cells (DC) biology is to understand how type I IFNs modulate the
immuno-regulatory properties of DC. In this review I will address this issue in light of the …

Innate immune recognition of pathogens triggers both immediate defenses against the
invading pathogens and the initiation of adaptive immune responses. Dendritic cells (DCs) …

Monocytes and dendritic cells (DCs), mononuclear phagocytes essential for immune
responses, develop from hematopoietic stem cells via monocyte-DC progenitors (MDPs) …