Identification of virulence-associated properties by comparative genome analysis of Streptococcus pneumoniae, S. pseudopneumoniae, S. mitis, three S. oralis …

M Kilian, H Tettelin - MBio, 2019 - Am Soc Microbiol
From a common ancestor, Streptococcus pneumoniae and Streptococcus mitis evolved in
parallel into one of the most important pathogens and a mutualistic colonizer of humans …

Parallel evolution of Streptococcus pneumoniae and Streptococcus mitis to pathogenic and mutualistic lifestyles

M Kilian, DR Riley, A Jensen, H Brüggemann… - MBio, 2014 - Am Soc Microbiol
The bacterium Streptococcus pneumoniae is one of the leading causes of fatal infections
affecting humans. Intriguingly, phylogenetic analysis shows that the species constitutes one …

Comparative Genomic Analyses of Streptococcus pseudopneumoniae Provide Insight into Virulence and Commensalism Dynamics

D Shahinas, CS Thornton, GS Tamber, G Arya… - PLoS …, 2013 - journals.plos.org
Streptococcus pseudopneumoniae (SPPN) is a recently described species of the viridans
group streptococci (VGS). Although the pathogenic potential of S. pseudopneumoniae …

Genomic characterization of the emerging pathogen Streptococcus pseudopneumoniae

G Garriss, P Nannapaneni, AS Simões, S Browall… - MBio, 2019 - Am Soc Microbiol
Streptococcus pseudopneumoniae is a close relative of the major human pathogen S.
pneumoniae. It is increasingly associated with lower-respiratory-tract infections (LRTI) and a …

Resolving Phylogenetic Relationships for Streptococcus mitis and Streptococcus oralis through Core- and Pan-Genome Analyses

IM Velsko, MS Perez, VP Richards - Genome biology and …, 2019 - academic.oup.com
Taxonomic and phylogenetic relationships of Streptococcus mitis and Streptococcus oralis
have been difficult to establish biochemically and genetically. We used core-genome …

Evolution of Streptococcus pneumoniae and Its Close Commensal Relatives

M Kilian, K Poulsen, T Blomqvist, LS Håvarstein… - PloS one, 2008 - journals.plos.org
Streptococcus pneumoniae is a member of the Mitis group of streptococci which, according
to 16S rRNA-sequence based phylogenetic reconstruction, includes 12 species. While other …

Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences

W Nasser, SB Beres, RJ Olsen… - Proceedings of the …, 2014 - National Acad Sciences
We sequenced the genomes of 3,615 strains of serotype Emm protein 1 (M1) group A
Streptococcus to unravel the nature and timing of molecular events contributing to the …

Population genetics and evolution of the pan-genome of Streptococcus pneumoniae

A Muzzi, C Donati - International Journal of Medical Microbiology, 2011 - Elsevier
The genetic variability in bacterial species is much larger than in other kingdoms of life. The
gene content between pairs of isolates can diverge by as much as 30% in species like …

A Pangenome Approach for Discerning Species-Unique Gene Markers for Identifications of Streptococcus pneumoniae and Streptococcus pseudopneumoniae

L Gonzales-Siles, R Karlsson, P Schmidt… - Frontiers in cellular …, 2020 - frontiersin.org
Correct identifications of isolates and strains of the Mitis-Group of the genus Streptococcus
are particularly difficult, due to high genetic similarity, resulting from horizontal gene transfer …

Conserved and specific features of Streptococcus pyogenes and Streptococcus agalactiae transcriptional landscapes

I Rosinski-Chupin, E Sauvage, A Fouet, C Poyart… - BMC genomics, 2019 - Springer
Abstract Background The human pathogen Streptococcus pyogenes, or group A
Streptococcus, is responsible for mild infections to life-threatening diseases. To facilitate the …