We report on the characterization and functional analysis of IFNγ of the goldfish. Quantitative
analysis indicated the highest expression of goldfish IFNγ in the spleen, with lower …

Unlike mammals, bony fish have two type II interferons, IFNγ and IFNγrel, whose pro-
inflammatory functions have not been fully characterized. To elucidate the distinct roles of …

Interferon gamma (IFN-γ) has important roles in both innate and adaptive immune
responses. This cytokine plays a very important role in defining Th1 immune response in all …

Two interferon gamma (IFN-γ) genes are expressed in immune cells of teleost fish and are
potentially implicated in B-and T-lymphocyte responses. IFN-γ-2 shows structural and …

Interferon gamma (IFN-γ) has important roles in both innate and adaptive immune
responses. In this study, the cDNA and genomic sequences of Atlantic cod IFN-γ were …

Interferon gamma (IFN-γ) is a T helper cell type 1 (Th1) cytokine that plays important roles in
almost all phases of immune and inflammatory responses. Although IFN-γ gene in large …

This is the first report of comprehensive functional analysis of an interleukin-10 in bony fish.
Quantitative expression analysis of goldfish IL-10 revealed the greatest mRNA levels in the …

Interferon gamma (IFN-γ) is a major component in immunological signaling and plays a key
role in resisting viral infection. In this study, we identified and characterized an IFN-γ gene …

We identified and characterized two isoforms of tumor necrosis factor-alpha (TNFα) from the
goldfish, TNFα-1 and TNFα-2. At the protein level, goldfish TNFα-1 and TNFα-2 were most …

Interferon gamma (IFN-γ) is a widely expressed cytokine that has potent antiviral and
immunomodulatory effects. The expression and bioactivity of IFN-γ have been reported in …