Interleukin 21 Reinvigorates the Antiviral Activity of Hepatitis B Virus (HBV)–Specific CD8+ T Cells in Chronic HBV Infection
L Tang, C Chen, X Gao, W Zhang, X Yan… - The Journal of …, 2019 - academic.oup.com
Background Strategies that target functional recovery of exhausted hepatitis B virus (HBV)–
specific CD8+ T cells are beneficial for viral control, but the potential for interleukin 21 (IL-21) …
specific CD8+ T cells are beneficial for viral control, but the potential for interleukin 21 (IL-21) …
TNF-α/IFN-γ profile of HBV-specific CD4 T cells is associated with liver damage and viral clearance in chronic HBV infection
H Wang, H Luo, X Wan, X Fu, Q Mao, X Xiang… - Journal of …, 2020 - Elsevier
Background & Aims The role of hepatitis B virus (HBV)-specific CD4 T cells in patients with
chronic HBV infection is not clear. Thus, we aimed to elucidate this in patients with chronic …
chronic HBV infection is not clear. Thus, we aimed to elucidate this in patients with chronic …
[PDF][PDF] Dysfunctional B‐cell activation in cirrhosis resulting from hepatitis C infection associated with disappearance of CD27‐Positive B‐cell population
H Doi, TK Iyer, E Carpenter, H Li, KM Chang… - …, 2012 - Wiley Online Library
Chronic hepatitis C virus (HCV) infection is a leading cause of cirrhosis and hepatocellular
carcinoma (HCC). Both advanced solid tumors and HCV have previously been associated …
carcinoma (HCC). Both advanced solid tumors and HCV have previously been associated …
Elevated IL-6 Receptor Expression on CD4+ T Cells contributes to the increased Th17 Responses in patients with Chronic Hepatitis B
F Zhang, S Yao, J Yuan, M Zhang, Q He, G Yang… - Virology journal, 2011 - Springer
Abstract Background Increased numbers of Interleukin-17-producing CD4+ T cells (Th17)
have been found in association with hepatitis B virus (HBV)-induced liver injury. However …
have been found in association with hepatitis B virus (HBV)-induced liver injury. However …
Increased IL-17-producing CD8+ T cell frequency predicts short-term mortality in patients with hepatitis B virus-related acute-on-chronic liver failure
G Zhang, T Zhang, Q Zhao, C Xie, C Lin… - … and Clinical Risk …, 2018 - Taylor & Francis
Background IL-17-producing CD8+ T (Tc17) cells promote inflammation and have been
identified in chronic hepatitis. However, the role of Tc17 cells in patients with hepatitis B …
identified in chronic hepatitis. However, the role of Tc17 cells in patients with hepatitis B …
The balance between intrahepatic IL-17+ T cells and Foxp3+ regulatory T cells plays an important role in HBV-related end-stage liver disease
Y Niu, H Liu, D Yin, R Yi, T Chen, H Xue, S Zhang… - BMC immunology, 2011 - Springer
Backgroud IL-17+ T helper cells and Foxp3+ regulatory T cells are CD4+ T helper cells with
reciprocally regulated differentiation and function. Their frequency and function vary in …
reciprocally regulated differentiation and function. Their frequency and function vary in …
Decrease of CD69 levels on TCR Vα7.2+CD4+ innate-like lymphocytes is associated with impaired cytotoxic functions in chronic hepatitis B virus-infected patients
Hepatitis B virus (HBV) infection is a major cause of chronic liver disease that may progress
to liver cirrhosis and hepatocellular carcinoma. Host immune responses represent the key …
to liver cirrhosis and hepatocellular carcinoma. Host immune responses represent the key …
TLR3 Activation of hepatic stellate cell line suppresses HBV replication in HepG2 cells
There is limited information about the role of hepatic stellate cells (HSCs) in the liver innate
immunity against hepatitis B virus (HBV) infection. We thus examined whether hepatic …
immunity against hepatitis B virus (HBV) infection. We thus examined whether hepatic …
[HTML][HTML] Interleukin-7 in patients with chronic hepatitis B may have effect on T follicular helper cells and specific cellular immunity
H Zhong, G Xibing, D Yaping, W Zheng, F Decai… - Hepatitis …, 2016 - ncbi.nlm.nih.gov
Background In patients with chronic hepatitis B (CHB), the relation of interkeukin-7 (IL-7) to
either the T follicular helper cells (Tfh cells) or to a specific cellular immune response is not …
either the T follicular helper cells (Tfh cells) or to a specific cellular immune response is not …
Identification of pro-inflammatory CD205+ macrophages in livers of hepatitis B virus transgenic mice and patients with chronic hepatitis B
L Yong, M Li, Y Gao, Y Deng, W Liu, D Huang… - Scientific Reports, 2017 - nature.com
Hepatic macrophages play a central role in disease pathogenesis during hepatitis B virus
(HBV) infection. Our previous study found that CD205+ macrophages in the liver of hepatitis …
(HBV) infection. Our previous study found that CD205+ macrophages in the liver of hepatitis …