Background: Activated hepatic stellate cells (aHSCs) regulate the function of immune cells
during liver fibrosis. As major innate cells in the liver, macrophages have inducible plasticity …

Dendritic cells (DCs) are antigen‐presenting cells with a central role in host immune
response. This study analyzed gene expression and DC function in hepatitis B virus (HBV) …

Abstract Background Both interleukin (IL)-17-secreting CD4+ T (Th17) and CD4+ CD25+
Foxp3+ T regulatory (Treg) cells have been shown to be associated with disease …

Background The role of interleukin-23 (IL-23) in monocyte-derived dendritic cells (MoDCs)
from hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) patients remains …

Chronic liver disease mediated by activation of hepatic stellate cells (HSCs) leads to liver
fibrosis. Here, we postulated that the immune regulatory properties of HSCs might promote …

Hepatitis C virus infection is a major cause of chronic liver disease. CD4+ T cells play a key
role in disease outcome. However, the critical functions and associated phenotypes of …

BACKGROUND. The clearance of hepatitis B surface antigen (HBsAg) loss, defined as
functional cure, is a clinical target in patients with chronic hepatitis B (CH). To understand …

T follicular helper cells (Tfh) provide help to B cells to support their activation, expansion and
differentiation. However, the role of Tfh cells in chronic HBV infection is poorly defined. The …

Background γδ T cells play an important role in infectious, autoimmune, or neoplastic
diseases. Here, a study was conducted to investigate the dynamic changes in phenotype …

CD8 T cell killing of hepatitis C virus (HCV)‐infected hepatocytes is thought to contribute to
liver damage during chronic HCV infection, whereas the participation of HCV‐nonspecific …