The relapsing peculiarity of Plasmodium vivax is one of the prime reasons for sustained
global malaria transmission. Global containment of P. vivax is more challenging and crucial …

Introduction: Relapses are important contributors to illness and morbidity in Plasmodium
vivax and P. ovale infections. Relapse prevention (radical cure) with primaquine is required …

Background Vivax malaria remains a major cause of morbidity in the subtropics. To
undermine the stability of the disease, drugs are required that prevent relapse and provide …

The hypnozoite reservoir of Plasmodium vivax represents both the greatest obstacle and
opportunity for ultimately eradicating this species. It is silent and cannot be diagnosed until it …

Initiatives to eradicate malaria have a good impact on P. falciparum malaria worldwide. P.
vivax, however, still presents significant difficulties. This is due to its unique biological traits …

In regions coendemic for P. vivax and P. falciparum, a unified treatment policy for malaria of
any parasitological cause is likely to confer the greatest individual and public health benefit …

The hypnozoite reservoir of Plasmodium vivax represents both the greatest obstacle and
opportunity for ultimately eradicating this species. It is silent and cannot be diagnosed until it …

Abstract Background Relapsing Plasmodium vivax infection results in significant morbidity
for the individual and is a key factor in transmission. Primaquine remains the only licensed …

The widespread use of primaquine (PQ) radical cure for P. vivax, is constrained by concerns
over its safety. We used routinely collected patient data to compare the overall morbidity and …

Background The optimal dosing of primaquine to prevent relapsing Plasmodium vivax
malaria in South Asia remains unclear. We investigated the efficacy and safety of different …