PEROXISOME proliferator-activated receptors (PPARs) are ligand-activated transcriptional
factors belonging to superfamily of nuclear hormone receptors related to retinoid, steroid …

PPARδ is the only member in the PPAR subfamily of nuclear receptors that is not a target of
current drugs. Animal studies demonstrate PPARδ activation exerts many favorable effects …

Obesity is a growing threat to global health by virtue of its association with insulin resistance,
glucose intolerance, hypertension, and dyslipidemia, collectively known as the metabolic …

The peroxisome proliferator-activated receptors (PPARs) alpha, delta and gamma are a
group of ligand-activated transcription factors that function as lipid sensors and govern …

Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors. They function as
ligand activated transcription factors. They exist in three isoforms, PPARα, PPARβ (formerly …

Peroxisome proliferator-activated receptors (PPARs) are the key transcription factors
regulating lipid metabolism and energy homeostasis. PPARα and PPARγ are known …

The development of new treatments for metabolic syndrome is urgent project for decreasing
the prevalence of coronary heart disease and diabetes mellitus in the advanced countries …

Peroxisome proliferator-activated receptors (PPARs) exert versatile biological effects,
notably in energy metabolism. During the last two decades, numerous studies have …

The peroxisome proliferator-activated receptor gamma (PPARγ), a member of the nuclear
hormone receptor superfamily has classically been characterized for its implications in …

Only a limited number of treatment options are available for insulin resistance, a major
cause of type 2 diabetes (T2D) and the metabolic syndrome. None adequately address the …