Bone regeneration using tissue engineered constructs requires strategies to effectively
stimulate vascularization within such a construct that is crucial for its supply and integration …

Regenerative engineering approaches utilizing biomimetic synthetic scaffolds provide
alternative strategies to repair and restore damaged bone. The efficacy of the scaffolds for …

Bone defects caused by diseases such as bone diseases, tumours, and traumas negatively
affect the lives of millions of people around the world. Bone tissue engineering offers a new …

Vascularization is a fundamental prerequisite for large bone construct development and
remains one of the main challenges of bone tissue engineering. Our current study presents …

Tissue engineering (TE)-based bone grafts are favorable alternatives to autografts and
allografts. Both biochemical properties and the architectural features of TE scaffolds are …

Abstract Three-dimensional (3D) printing is a novel process used to manufacture bone
tissue engineered scaffolds. This process allows for easy control of the architecture at the …

Three-dimensional (3D) printed scaffolds provide a promising prospective for application in
bone tissue engineering. 3D printed scaffolds with micro-and nano-fibrous structures that …

Scaffolds functionalized with biomolecules have been developed for bone regeneration but
inducing the regeneration of complex structured bone with neovessels remains a challenge …

Reconstruction of patient-specific scaffolds to repair uniquely shaped bone defects remains
a major clinical challenge in tissue engineering. Recently, three-dimensional (3D) printed …

Tumor resection and treatment of trauma-related regional large bone defects have major
challenges in the field of orthopedics. Scaffolds that treat bone defects are the focus of bone …