Mimicking nanofibrous hybrid bone substitute for mesenchymal stem cells differentiation into osteogenesis

C Gandhimathi, J Venugopal… - Macromolecular …, 2013 - Wiley Online Library
Mimicking hybrid extracellular matrix is one of the main challenges for bone tissue
engineering (BTE). Biocompatible polycaprolactone/poly (α, β)‐dl‐aspartic acid/collagen …

VEGF-Loaded Heparinised Gelatine-Hydroxyapatite-Tricalcium Phosphate Scaffold Accelerates Bone Regeneration via Enhancing Osteogenesis-Angiogenesis …

X Chen, CY Gao, XY Chu, CY Zheng… - … in Bioengineering and …, 2022 - frontiersin.org
Background: Bone tissue defect, one of the common orthopaedicdiseases, is traumatizing
and affects patient's lifestyle. Although autologous and xenograft bone transplantations are …

Osteoporotic Bone Regeneration via Plenished Biomimetic PLGA Scaffold with Sequential Release System

JK Lee, DS Kim, SY Park, JW Jung, SW Baek, S Lee… - Small, 2024 - Wiley Online Library
Achieving satisfactory bone tissue regeneration in osteoporotic patients with ordinary
biomaterials is challenging because of the decreased bone mineral density and aberrant …

Determination of cytocompatibility and osteogenesis properties of in situ forming collagen-based scaffolds loaded with bone synthesizing drug for bone tissue …

NA Elkasabgy, AA Mahmoud… - International Journal of …, 2018 - Taylor & Francis
Bone tissue engineering using in situ forming 3D scaffolds can be an alternative to surgically
treated scaffolds. This work aimed to develop in situ forming scaffolds using poly (lactic-co …

[HTML][HTML] Lotus seedpod-inspired internal vascularized 3D printed scaffold for bone tissue repair

X Han, M Sun, B Chen, Q Saiding, J Zhang, H Song… - Bioactive materials, 2021 - Elsevier
In the field of bone defect repair, 3D printed scaffolds have the characteristics of
personalized customization and accurate internal structure. However, how to construct a …

Synergistic interplay between human MSCs and HUVECs in 3D spheroids laden in collagen/fibrin hydrogels for bone tissue engineering

DN Heo, M Hospodiuk, IT Ozbolat - Acta biomaterialia, 2019 - Elsevier
Stem cell encapsulation in hydrogels has been widely employed in tissue engineering,
regenerative medicine, organ-on-a-chip devices and gene delivery; however, fabrication of …

Fabrication and characterization of the 3D‐printed polycaprolactone/fish bone extract scaffolds for bone tissue regeneration

SY Heo, SC Ko, GW Oh, N Kim, IW Choi… - … Research Part B …, 2019 - Wiley Online Library
Fish bone extract (FBE) containing a trioligopeptide (FBP‐KSA, Lys‐Ser‐Ala) isolated from
Johnius belengerii could induce osteogenic activities on MC3T3‐E1 pre‐osteoblasts in our …

Mechanical–chemical coupled modeling of bone regeneration within a biodegradable polymer scaffold loaded with VEGF

L Wang, Q Shi, Y Cai, Q Chen, X Guo, Z Li - Biomechanics and Modeling …, 2020 - Springer
Repairing critical-size bone defects with engineered scaffolds remains a challenge in
orthopedic practice. Insufficient vascularization is a major reason causing the failure of bone …

[HTML][HTML] Fabrication of a bio-instructive scaffold conferred with a favorable microenvironment allowing for superior implant osseointegration and accelerated in situ …

Y He, W Wang, S Lin, Y Yang, L Song, Y Jing, L Chen… - Bioactive Materials, 2022 - Elsevier
The potential translation of bio-inert polymer scaffolds as bone substitutes is limited by the
lack of neovascularization upon implantation and subsequently diminished ingrowth of host …

Osteogenic and angiogenic potentials of the cell-laden hydrogel/mussel-inspired calcium silicate complex hierarchical porous scaffold fabricated by 3D bioprinting

YW Chen, YF Shen, CC Ho, J Yu, YHA Wu… - Materials Science and …, 2018 - Elsevier
Abstract 3D printing has been popularly used in the bone tissue engineering, as many of the
biomaterials for this field of study can be prepared for and produced from this additive …