The currently available diphtheria-tetanus-whole-cell pertussis (DTP) vaccines are
associated with a variety of problems, including undesirable side effects and inconsistent …

• Objective—To compare the reactogenicity and immunogenicity of a diphtheria and tetanus
toxoids and two-component acellular pertussis (ADTP) vaccine with a US-licensed whole …

A double blind, randomized, controlled trial compared the safety and immunogenicity of an
acellular pertussis vaccine formulated at Lederle using the Takeda acellular pertussis …

Whole cell pertussis vaccines used in the United States have brought about a dramatic
decline in the reported morbidity and mortality caused by pertussis, from a maximum of more …

A tricomponent acellular pertussis vaccine containing pertussis toxoid, filamentous
hemagglutinin, and pertactin combined with diphtheria and tetanus toxoids (DTPa) was …

An acellular pertussis vaccine principally containing two purified pertussis antigens,
filamentous hemagglutinin and lymphocytosis-promoting factor, combined with diphtheria …

Diphtheria and tetanus toxoids (DT) vaccine should be given to children at 2, 4 and 6
months of age when there are contraindications to the administration of pertussis vaccine …

• Although the conventionalBordetella pertussisvaccine, which consists of killed whole
organisms, has been shown to be effective in preventing disease, it has been associated …

We compared immunogenicity and reactogenicity of a single dose of DTaP vaccine
(containing tetanus and diphtheria toxoids and four acellular pertussis antigens) with …

Recently, concern has been voiced about the potential effect that antigenic divergence of
circulating strains of Bordetella pertussis might have on the efficacy of pertussis vaccines. In …