Despite wide vaccination coverage with efficacious vaccines, pertussis is still not under
control in any country. Two types of vaccines are available for the primary vaccination series …

We compared the reactions and immunogenicity of DT acellular pertussis (DTaP) vaccines
containing pertussis toxoid (PT) and filamentous haemagglutinin (FHA)(2-component DTaP) …

Background In 1993 there was a resurgence of pertussis in the United States. Altogether,
6335 cases were reported, the most in 26 years. Methods Using active microbiologic …

• Objective.—To compare the immunogenicity and reactogenicity of a two-component
acellular pertussis vaccine (BIKEN) with whole-cell diphtheria and tetanus toxoids and …

Publisher Summary This chapter describes Bordetella pertussis and discusses recent
advances in the development of pertussis vaccines. Bordetella pertussis is the pathogen that …

Objective. To compare the immunogenicity of a licensed conventional whole-cell (WCL) and
13 diphtheria-tetanus-acellular pertussis (DTaP) vaccines that differed in source, method of …

In 1974, the authors reported the isolation and characterization of protective antigens
ofBordetella pertussis in mice. With this information, an acellular pertussis vaccine was …

We assessed the kinetics of the humoral immune response to pertussis antigens following
vaccination of health care personnel with adult tetanus-diphtheria-acellular pertussis …

Three monoclonal antibodies to pertussis toxin were characterized and used to investigate
its role in immunity. Antibody affinity correlated with toxin neutralization in in vivo and in vitro …

Objective. We compared the diphtheria and tetanus toxoids and bicomponent acellular
pertussis vaccine (DTaP) responses in Japanese and United States infants. Design. This …