AFTER digesting this sobering fact, one might reasonably wonder—what about the other
87% of the 65+ age group? Although most older Americans are living without cognitive …

Characterizing the cognitive declines associated with aging, and differentiating them from
the effects of disease in older adults, are important goals for human neuroscience …

Human neuroimaging research on cognitive aging has brought significant advances to our
understanding of the neural mechanisms underlying age-related cognitive decline and …

As the global population faces a progressive shift towards a higher median age,
understanding the mechanisms underlying healthy brain ageing has become of paramount …

The past 25 years have provided a rich discovery of at least four fundamental patterns that
represent structural and functional brain aging across multiple cognitive domains. Of the …

The natural history of life span cognitive performance and its late‐life determinants have
been studied from an array of perspectives. Significant insights come from psychological …

Abstract The World Health Organization (WHO) aims to improve our understanding of the
factors that promote healthy cognitive aging and combat dementia. Aging theories that …

Over the last several years, neuroscientists have been increasingly using neuroimaging
techniques to unravel the neurobiology underlying cognitive aging, and in more recent years …

Recent advances in clinical neuroscience, brain imaging and genetics challenge
pathophysiological hypothesis of neurodegeneration and cognitive aging dominating the …

Across the lifespan, the human body and brain endure the impact of a plethora of
exogenous and endogenous factors that determine the health outcome in old age. The …