Immune regulation by parasites is a global concept that includes suppression, diversion,
and conversion of the host immune response to the benefit of the pathogen. While many …

Helminth parasites are complex metazoans that belong to different taxonomic families but
that collectively share the capacity to downregulate the host immune response directed …

Helminths are multicellular eukaryotic parasites that infect over one quarter of the world's
population. Through coevolution with the human immune system, these organisms have …

Helminths are extraordinarily successful parasites due to their ability to modulate the host
immune response. They have evolved a spectrum of immunomodulatory molecules that are …

Helminths are masterful immunoregulators. A characteristic feature of helminth infection is a
Th2-dominated immune response, but stimulation of immunoregulatory cell populations …

Although helminth infections are characteristically associated with Th2‐mediated responses
that include the production of the prototypical cytokines IL‐4, IL‐5 and IL‐13 by CD 4+ cells …

The field of infectious disease immunology is at an exciting intersection with new concepts in
immune regulation meeting with the dynamics of infectious diseases. We discuss how the …

Helminth parasite infections are associated with a battery of immunomodulatory
mechanisms that affect all facets of the host immune response to ensure their persistence …

Parasitic infections are a major theme in the “hygiene hypothesis”, as allergies and
autoimmune diseases are less prevalent in countries with higher burdens of helminths and …

The vertebrate immune system has evolved in concert with a broad range of infectious
agents, including ubiquitous helminth (worm) parasites. The constant pressure of helminth …