Technical progress in materials science and bioprinting has for the past few decades
fostered considerable advances in medicine. More recently, the understanding of the …

Micro-and nanoscale technologies have emerged as powerful tools in the fabrication of
engineered tissues and organs. Here we focus on the application of these techniques to …

In vitro-generated tissues hold significant promise in modern biology since they can
potentially mimic physiological and pathological tissues. However, these are currently …

Organoids form through self-organization processes in which initially homogeneous
populations of stem cells spontaneously break symmetry and undergo in-vivo-like pattern …

Mimicking natural tissue structure is crucial for engineered tissues with intended
applications ranging from regenerative medicine to biorobotics. Native tissues are highly …

The control of multicellular systems in general and of tissue formation in particular is a
frontier for regenerative medicine and basic biological research. Current manipulations of …

Understanding the principles of biological self-assembly is indispensable for developing
efficient strategies to build living tissues and organs. We exploit the self-organizing capacity …

Nature has evolved to grow and regenerate tissues and organs using self-assembling
processes capable of organizing a wide variety of molecular building-blocks at multiple size …

Biofabrication of living structures with desired topology and functionality requires the
interdisciplinary effort of practitioners of the physical, life and engineering sciences. Such …

Tissue morphogenesis occurs in a complex physicochemical microenvironment with limited
experimental accessibility. This often prevents a clear identification of the processes that …