Redox signaling in the gastrointestinal tract
S Pérez, R Taléns-Visconti, S Rius-Pérez… - Free Radical Biology …, 2017 - Elsevier
Redox signaling regulates physiological self-renewal, proliferation, migration and
differentiation in gastrointestinal epithelium by modulating Wnt/β-catenin and Notch …
differentiation in gastrointestinal epithelium by modulating Wnt/β-catenin and Notch …
Intestinal redox biology and oxidative stress
ML Circu, TY Aw - Seminars in cell & developmental biology, 2012 - Elsevier
The intestinal epithelium sits at the interface between an organism and its luminal
environment, and as such is prone to oxidative damage induced by luminal oxidants …
environment, and as such is prone to oxidative damage induced by luminal oxidants …
Control and dysregulation of redox signalling in the gastrointestinal tract
EL Campbell, SP Colgan - Nature Reviews Gastroenterology & …, 2019 - nature.com
Redox signalling in the gastrointestinal mucosa is held in an intricate balance. Potent
microbicidal mechanisms can be used by infiltrating immune cells, such as neutrophils, to …
microbicidal mechanisms can be used by infiltrating immune cells, such as neutrophils, to …
Oxidative stress in inflammation‐based gastrointestinal tract diseases: Challenges and opportunities
YJ Kim, EH Kim, KB Hahm - Journal of gastroenterology and …, 2012 - Wiley Online Library
Oxygen free radicals in excessively high amounts are all very reactive chemically and can
impose a detrimental influence on living organisms by provoking “oxidative stress” that can …
impose a detrimental influence on living organisms by provoking “oxidative stress” that can …
Redox biology of the intestine
ML Circu, TY Aw - Free radical research, 2011 - Taylor & Francis
The intestinal tract, known for its capability for self-renew, represents the first barrier of
defence between the organism and its luminal environment. The thiol/disulfide redox …
defence between the organism and its luminal environment. The thiol/disulfide redox …
Oxidative stress and redox signaling mechanisms of inflammatory bowel disease: updated experimental and clinical evidence
H Zhu, YR Li - Experimental Biology and Medicine, 2012 - journals.sagepub.com
Inflammatory bowel disease (IBD) comprises primarily the chronic relapsing inflammatory
disorders, Crohn's disease and ulcerative colitis, with the former affecting any part of the …
disorders, Crohn's disease and ulcerative colitis, with the former affecting any part of the …
Inflammatory bowel disease: mechanisms, redox considerations, and therapeutic targets
F Biasi, G Leonarduzzi, PI Oteiza… - Antioxidants & redox …, 2013 - liebertpub.com
Oxidative stress is thought to play a key role in the development of intestinal damage in
inflammatory bowel disease (IBD), because of its primary involvement in intestinal cells' …
inflammatory bowel disease (IBD), because of its primary involvement in intestinal cells' …
Chronic inflammatory disorders and their redox control: from molecular mechanisms to therapeutic opportunities
V Chiurchiu, M Maccarrone - Antioxidants & redox signaling, 2011 - liebertpub.com
A chronic inflammatory disease is a condition characterized by persistent inflammation. A
number of human pathologies fall into this category, and a great deal of research has been …
number of human pathologies fall into this category, and a great deal of research has been …
Cellular redox: a modulator of intestinal epithelial cell proliferation
TY Aw - Physiology, 2003 - journals.physiology.org
Mucosal proliferation, together with differentiation and apoptosis, are a continuous
homeostatic process in the intestinal epithelium. The glutathione/glutathione disulfide redox …
homeostatic process in the intestinal epithelium. The glutathione/glutathione disulfide redox …
ROS in gastrointestinal inflammation: rescue or sabotage?
The intestine is composed of many distinct cell types that respond to commensal microbiota
or pathogens with immune tolerance and proinflammatory signals respectively. ROS …
or pathogens with immune tolerance and proinflammatory signals respectively. ROS …