Comparative analysis of biofilm models to determine the efficacy of antimicrobials
EK Stuermer, M Besser, F Brill, M Geffken… - International Journal of …, 2021 - Elsevier
Biofilms are one of the greatest challenges in today's treatment of chronic wounds. While
antimicrobials kill platonic bacteria within seconds, they are rarely able to harm biofilms. In …
antimicrobials kill platonic bacteria within seconds, they are rarely able to harm biofilms. In …
[HTML][HTML] 3D Biofilm Models Containing Multiple Species for Antimicrobial Testing of Wound Dressings
K Reddersen, J Tittelbach, C Wiegand - Microorganisms, 2022 - mdpi.com
The treatment of chronic wounds presents a major challenge in medical care. In particular,
the effective treatment of bacterial infections that occur in the form of biofilms is of crucial …
the effective treatment of bacterial infections that occur in the form of biofilms is of crucial …
[HTML][HTML] Development of an implantable three-dimensional model of a functional pathogenic multispecies biofilm to study infected wounds
C Cárdenas-Calderón, V Veloso-Giménez… - Scientific Reports, 2022 - nature.com
Chronic wounds cannot heal due to impairment of regeneration, mainly caused by the
persistent infection of multispecies biofilms. Still, the effects of biofilm wound infection and its …
persistent infection of multispecies biofilms. Still, the effects of biofilm wound infection and its …
In Vitro and In Vivo Biofilm Wound Models and Their Application
G Brackman, T Coenye - … in Microbiology, Infectious Diseases and Public …, 2016 - Springer
Chronic wounds are wounds which are detained in one or more phases of normal wound
healing. It is estimated that 1–2% of the population of developed countries will experience a …
healing. It is estimated that 1–2% of the population of developed countries will experience a …
[HTML][HTML] Assessing the inflammatory response to in vitro polymicrobial wound biofilms in a skin epidermis model
Wounds can commonly become infected with polymicrobial biofilms containing bacterial and
fungal microorganisms. Microbial colonization of the wound can interfere with sufficient …
fungal microorganisms. Microbial colonization of the wound can interfere with sufficient …
A novel chronic wound biofilm model sustaining coexistence of Pseudomonas aeruginosa and Staphylococcus aureus suitable for testing of antibiofilm effect of …
X Chen, J Lorenzen, Y Xu, M Jonikaite… - Wound Repair and …, 2021 - Wiley Online Library
Chronic wounds are a large burden to patients and healthcare systems. Biofilm infections in
chronic wounds are crucial factors leading to non‐healing of wounds. It is important to study …
chronic wounds are crucial factors leading to non‐healing of wounds. It is important to study …
Anti-biofilm activity of antimicrobial hypochlorous wound irrigation solutions compared to common wound antiseptics and bacterial resilience in an innovative in-vitro …
Background Biofilms pose a relevant factor for wound healing impairment in chronic
wounds. With 78% of all chronic wounds being affected by biofilms, research in this area is …
wounds. With 78% of all chronic wounds being affected by biofilms, research in this area is …
[PDF][PDF] Dressings and biofilms: interpreting evidence from in vitro biofilm models
K Bourdillon - Wounds Int, 2016 - researchgate.net
In vitro models are used to study biofilm behaviour. However, the model and assay
conditions can substantially affect results. This review discusses published in vitro biofilm …
conditions can substantially affect results. This review discusses published in vitro biofilm …
Human skin biofilm model: Translational impact on swabbing and debridement
M Dietrich, M Besser, ES Debus… - Journal of Wound …, 2023 - magonlinelibrary.com
Objective: Wound biofilms are one of the greatest challenges in the therapy of hard-to-heal
(chronic) wounds, as potent antimicrobial substances fail to eradicate bacteria within short …
(chronic) wounds, as potent antimicrobial substances fail to eradicate bacteria within short …
A multimodel regime for evaluating effectiveness of antimicrobial wound care products in microbial biofilms
JJ Stoffel, PL Kohler Riedi… - Wound Repair and …, 2020 - Wiley Online Library
Microbial biofilms have become increasingly recognized as a cause of wound chronicity.
There are several topical antimicrobial wound care products available for use; however …
There are several topical antimicrobial wound care products available for use; however …