Background Breast cancer surgeons struggle with differentiating healthy tissue from cancer
at the resection margin during surgery. We report on the feasibility of using diffuse …

Recognition of the tumor during breast-conserving surgery (BCS) can be very difficult and
currently a robust method of margin assessment for the surgical setting is not available. As a …

Diffuse reflectance spectroscopy (DRS) is a promising new technique for breast cancer
diagnosis. However, inter-patient variation due to breast tissue heterogeneity may interfere …

There continues to be a significant clinical need for rapid and reliable intraoperative margin
assessment during cancer surgery. Here we describe a portable, quantitative, optical fiber …

In an ongoing effort to address the clear clinical unmet needs surrounding breast conserving
surgery (BCS), our group has developed a next-generation multiplexed optical-fiber-based …

Importance Cancers of the upper gastrointestinal tract remain a major contributor to the
global cancer burden. The accurate mapping of tumor margins is of particular importance for …

This ex-vivo study evaluates the feasibility of diffuse reflectance spectroscopy (DRS) for
discriminating tumor from healthy tissue, with the aim to develop a technology that can …

Diffuse reflectance spectroscopy (DRS) is a well-established method to quantitatively
distinguish between benign and cancerous tissue for tumor margin assessment. Current …

Breast conserving surgery, in which the breast tumor and the surrounding normal tissue are
removed, is the primary mode of treatment for invasive and in situ carcinomas of the breast …

Background In colorectal cancer surgery there is a delicate balance between complete
removal of the tumor and sparing as much healthy tissue as possible. Especially in rectal …