The bovine brain A1-adenosine receptor was purified 8000-fold by affinity chromatography
on xanthine-amine-congener (XAC)-Sepharose. Addition of a 120-fold molar excess of a …

The purified bovine brain A1-adenosine receptor has previously been shown to discriminate
among closely related G protein alpha-subunits. To obtain analogous information for the …

A 1 adenosine receptors and guanine nucleotide-binding proteins (G proteins) solubilized
with 3-[(3-cholamidopropyl) dimethylammonio]-1-propanesulfonate have been co-purified …

A membrane protein identified in cortical brain membranes and termed 'coupling cofactor',
modulates G protein-coupling of the A1-adenosine receptor by reducing the catalytic …

The effects of guanine nucleotides, NaCl, and solubilization on the interaction of antagonists
and agonists with the A1 adenosine receptor of bovine brain membranes were studied using …

The ability of the bovine brain A1-adenosine receptor to discriminate between different G
protein subtypes was tested using G protein alpha-subunits synthesized in Escherichia coli …

Full and partial agonists of the A1 adenosine receptor were characterized with respect to
their influence on G protein activation and their thermodynamic parameters of receptor …

Guanine nucleotides such as guanosine 5'-(3-O-thio) triphosphate (GTP gamma S) have
been found to increase the binding of antagonists to adenosine A1 receptors. This response …

Signal transduction by A1 adenosine receptors was investigated by measuring the
modulation by adenosine agonists of guanosine-5'-O-(3-[35S] thio) triphosphate ([35S] GTP …

This study was designed to provide evidence for the coupling of A2-adenosine receptor with
stimulatory guanine nucleotide-binding protein (Gs) protein and adenylate cyclase in bovine …