Metabolomics quantitatively measures metabolites in a given biological system and
facilitates the understanding of physiological and pathological activities. With the recent …

With recent advances in mass spectrometry, there is an increased interest in data-
independent acquisition (DIA) techniques for metabolomics. With DIA technique, all …

In recent years, metabolomics has emerged as a pivotal approach for the holistic analysis of
metabolites in biological systems. The rapid progress in analytical equipment, coupled to the …

The metabolome is composed of a vast number of small-molecule metabolites that exhibit a
diversity of physical and chemical properties and exist over a wide dynamic range in …

SWATH-MS-based data-independent acquisition mass spectrometry (DIA-MS) technology
has been recently developed for untargeted metabolomics due to its capability to acquire all …

Existing data acquisition modes such as full-scan, data-dependent (DDA), and data-
independent acquisition (DIA) often present limited capabilities in capturing metabolic …

Metabolomics is the systematic study of all the metabolites present within a biological
system, which consists of a mass of molecules, having a variety of physical and chemical …

Metabolomics aims at the comprehensive assessment of a wide range of endogenous
metabolites and attempts to identify and quantify the attractive metabolites in a given …

A current and significant limitation to metabolomics is the large-scale, high-throughput
conversion of raw chromatographically coupled mass spectrometry datasets into organized …

Metabolite identification is one of the major bottlenecks in liquid chromatography-mass
spectrometry (LC-MS)-based untargeted metabolomics owing to the difficulty of acquiring …