[PDF][PDF] Engagement of specific innate immune signaling pathways during Porphyromonas gingivalis induced chronic inflammation and atherosclerosis

G FC III - Front. Biosci., 2008 - article.imrpress.com
Introduction 3. Epidemiological Associations Of Infection With Systemic Diseases 3.1.
Infectious Agents And Association With Atherosclerosis 3.2. Periodontal Disease And P …

Pathogen‐induced inflammation at sites distant from oral infection: bacterial persistence and induction of cell‐specific innate immune inflammatory pathways

C Hayashi, CV Gudino, FC Gibson Iii… - Molecular oral …, 2010 - Wiley Online Library
A hallmark of infection with the gram‐negative pathogen Porphyromonas gingivalis is the
induction of a chronic inflammatory response. P. gingivalis induces a local chronic …

Association between Porphyromonas Gingivalis and systemic diseases: Focus on T cells-mediated adaptive immunity

C Li, R Yu, Y Ding - Frontiers in Cellular and Infection Microbiology, 2022 - frontiersin.org
The association between periodontal disease and systemic disease has become a research
hotspot. Porphyromonas gingivalis (P. gingivalis), a crucial periodontal pathogen, affects the …

Innate Immune Signaling and Porphyromonas gingivalis-accelerated Atherosclerosis

FC Gibson III, H Yumoto, Y Takahashi… - Journal of dental …, 2006 - journals.sagepub.com
Periodontal diseases are a group of diseases that lead to erosion of the hard and soft
tissues of the periodontium, which, in severe cases, can result in tooth loss. Anecdotal …

Porphyromonas gingivalis suppresses adaptive immunity in periodontitis, atherosclerosis, and Alzheimer's disease

I Olsen, MA Taubman, SK Singhrao - Journal of oral microbiology, 2016 - Taylor & Francis
Porphyromonas gingivalis, a keystone pathogen in chronic periodontitis, has been found to
associate with remote body organ inflammatory pathologies, including atherosclerosis and …

Macrophages: A communication network linking Porphyromonas gingivalis infection and associated systemic diseases

J Lin, D Huang, H Xu, F Zhan, XL Tan - Frontiers in Immunology, 2022 - frontiersin.org
Porphyromonas gingivalis (P. gingivalis) is a Gram-negative anaerobic pathogen that is
involved in the pathogenesis of periodontitis and systemic diseases. P. gingivalis has …

Altered T-Cell Responses by the Periodontal Pathogen Porphyromonas gingivalis

H Khalaf, T Bengtsson - 2012 - journals.plos.org
Several studies support an association between the chronic inflammatory diseases
periodontitis and atherosclerosis with a crucial role for the periodontal pathogen …

Porphyromonas gingivalis regulates atherosclerosis through an immune pathway

Q Ruan, P Guan, W Qi, J Li, M Xi, L Xiao… - Frontiers in …, 2023 - frontiersin.org
Atherosclerosis (AS) is a chronic inflammatory disease, involving a pathological process of
endothelial dysfunction, lipid deposition, plaque rupture, and arterial occlusion, and is one of …

Porphyromonas gingivalis mediated periodontal disease and atherosclerosis: disparate diseases with commonalities in pathogenesis through TLRs

FC Gibson Iii, CA Genco - Current pharmaceutical design, 2007 - ingentaconnect.com
Toll-like receptors (TLRs) are a group of pathogen-associated molecular pattern receptors,
which play an important role in innate immune signaling in response to microbial infection. It …

Intracellular Signaling and Cytokine Induction upon Interactions of Porphyromonas gingivalis Fimbriae with Pattern‐Recognition Receptors

G Hajishengallis, H Sojar, RJ Genco… - Immunological …, 2004 - Taylor & Francis
Toll‐like receptors (TLRs) and other pattern‐recognition receptors (PRRs) of the innate
immune system form functional receptor complexes that recognize and respond to pathogen …