Aims MMPs contribute to atherosclerotic plaque progression and instability, but the relative
potency of their endogenous tissue inhibitors of metalloproteinases (TIMPs) as protective …

Objective—Atherosclerosis is considered to be a chronic inflammatory disease and many
cytokines participate in the development of atherosclerosis. We focused on the role of …

Matrix remodeling plays an important role in the physiological and pathological remodeling
of blood vessels. We specifically investigated the role of matrix metalloproteinase (MMP)-9 …

Matrix metalloproteinase‐9 (MMP‐9) belongs to the MMP family and has been widely
investigated. Excessive MMP‐9 expression can enhance extracellular matrix degradation …

Objective Patients with systemic lupus erythematosus (SLE) have a notable increase in
atherothrombotic cardiovascular disease (CVD) which is not explained by the Framingham …

Objective—Although IL-18 has been implicated in atherosclerotic lesion development, little
is known about its role in advanced atherosclerotic plaques. This study aims to assess the …

Background—Although it has been demonstrated that matrix metalloproteinases (MMPs)
play an important role in the arterial remodeling in atherosclerosis and restenosis, it is not …

Understanding the pathophysiology of atherogenesis and the progression of atherosclerosis
have been major goals of cardiovascular research during the previous decades. However …

A role of interferon-γ is suggested in early development of atherosclerosis. However, the role
of interferon-γ in progression and destabilization of advanced atherosclerotic plaques …

Objective—Whereas growth factors, via their ability to stimulate vascular smooth muscle cell
(VSMC) proliferation and migration, have been thought to play a permissive role in …