The tetrodotoxin-resistant (TTX-R) voltage-gated sodium channel SNS/PN3 and the newly
discovered NaN/SNS2 are expressed in sensory neurones, particularly in nociceptors …

Two tetrodotoxin-resistant voltage-gated sodium channels, SNS/PN3 and SNS2/NaN, have
been described recently in small-diameter sensory neurones of the rat, and play a key role …

The novel sodium channel PN3/α-SNS, which was cloned from a rat dorsal root ganglion
(DRG) cDNA library, is expressed predominantly in small sensory neurons and may …

Alterations in sodium channel expression and function have been suggested as a key
molecular event underlying the abnormal processing of pain after peripheral nerve or tissue …

Neuropathic pain may be produced, at least in part, by the increased activity of primary
afferent neurons. Studies have suggested that an accumulation of voltage-gated sodium …

Many damage-sensing neurons express tetrodotoxin (TTX)-resistant voltage-gated sodium
channels. Here we examined the role of the sensory-neuron-specific (SNS) TTX-resistant …

Voltage‐gated sodium channels underlie the generation of action potentials in excitable
cells. Various sodium channel isoforms have been cloned, functionally expressed and …

Increased voltage-gated sodium channel activity may contribute to the hyperexcitability of
sensory neurons in inflammatory and neuropathic pain states. We examined the levels of the …

We have examined the distribution of the sensory neuron‐specific Na+ channel Nav1. 8
(SNS/PN3) in nociceptive and non‐nociceptive dorsal root ganglion (DRG) neurons and …

Tetrodotoxin-resistant sodium currents contribute to the somal and axonal sodium currents
of small diameter primary sensory neurons, many of which are nociceptive. NaN is a recently …