Cell swelling has been shown to cause activation of a variety of cardiac sarcolemmal ionic
conductances including potassium channels. The aim of this study was to investigate the …

The aim of the present study was to define the cellular mechanisms underlying changes in
K+ channel function in the failing heart after myocardial infarction. Rats with left coronary …

Action potentials and ECGs were recorded from isolated guinea pig hearts during low flow
(10% of control) and zero flow myocardial “ischaemia” and during subsequent reperfusion …

To examine the impact of hypokalemia on cardiac electrical stability, the thresholds for
repetitive extrasystole and ventricular fibrillation were determined before and after …

Despite high efficacy, electrical defibrillation shocks can fail or ventricular fibrillation (VF) is
reinitiated after the application of the initial shock. The goal of this study was to determine …

M yocardial ischaemia leads to a cascade of metabolic and electrophysiological events
which are interrelated and are caused by reduced availability of oxygen and substrate, by …

Interactions of potassium and antiarrhythmic agents on ventricular myocardial
electrophysiology were studied in 25 isolated, perfused rabbit hearts by utilizing an …

The derangements of cardiac rhythm that result from occlusion of coronary arteries caught
the attention of the earliest experimenters in the field. By the time of the studies of Porter1 in …

The cellular electrophysiologic consequences of both regional and global experimental
ischemia and reperfusion were studied in the isolated cat myocardium, using conventional …

Ventricular tachycardia was induced in the intact non-ischaemic pig heart by intramyocardial
or intracoronary infusions of noradrenaline or N6, O2′-dibutyryl-cAMP. The chemically …