Heterologous prime-boost: breaking the protective immune response bottleneck of COVID-19 vaccine candidates

Q He, Q Mao, C An, J Zhang, F Gao, L Bian… - Emerging microbes & …, 2021 - Taylor & Francis
ABSTRACT COVID-19 vaccines emerging from different platforms differ in efficacy, duration
of protection, and side effects. To maximize the benefits of vaccination, we explored the …

Mitigating Covid-19 in the face of emerging virus variants, breakthrough infections and vaccine hesitancy

A Haque, AB Pant - Journal of autoimmunity, 2022 - Elsevier
The emergence and rapid global spread of the new Delta and, more recently, Omicron
variants of SARS-CoV-2 pose a daunting public health emergency. Being an RNA virus, the …

COVID-19 vaccines: current understanding on immunogenicity, safety, and further considerations

Q He, Q Mao, J Zhang, L Bian, F Gao, J Wang… - Frontiers in …, 2021 - frontiersin.org
The world has entered the second wave of the COVID-19 pandemic, and its intensity is
significantly higher than that of the first wave of early 2020. Many countries or regions have …

COVID-19 vaccines and decreased transmission of SARS-CoV-2

A Vitiello, F Ferrara, V Troiano, R La Porta - Inflammopharmacology, 2021 - Springer
A massive COVID-19 vaccination campaign is underway worldwide. Epidemiological data
from studies indicate excellent efficacy and safety profile for COVID-19 vaccines. However …

Immune responses during COVID-19 infection

C Melenotte, A Silvin, AG Goubet, I Lahmar… - …, 2020 - Taylor & Francis
Over the past 16 years, three coronaviruses (CoVs), severe acute respiratory syndrome CoV
(SARS-CoV) in 2002, Middle East respiratory syndrome CoV (MERS-CoV) in 2012 and …

Pre-existing SARS-CoV-2 immunity influences potency, breadth, and durability of the humoral response to SARS-CoV-2 vaccination

G Mantus, LE Nyhoff, VV Edara, VI Zarnitsyna… - Cell Reports …, 2022 - cell.com
The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic
highlights the importance of determining the breadth and durability of humoral immunity to …

Lessons for COVID-19 immunity from other coronavirus infections

A Sariol, S Perlman - Immunity, 2020 - cell.com
A key goal to controlling coronavirus disease 2019 (COVID-19) is developing an effective
vaccine. Development of a vaccine requires knowledge of what constitutes a protective …

Humoral and cellular immunity and the safety of COVID-19 vaccines: a summary of data published by 21 May 2021

K Xu, L Dai, GF Gao - International Immunology, 2021 - academic.oup.com
Abstract Coronavirus disease 2019 (COVID-19) has caused millions of deaths, and serious
consequences to public health, economies and societies. Rapid responses in vaccine …

Cell-mediated immune responses to COVID-19 infection

A Guihot, E Litvinova, B Autran, P Debré… - Frontiers in …, 2020 - frontiersin.org
An unprecedented outbreak of pneumonia caused by a novel coronavirus (CoV),
subsequently termed COVID-19 by the World Health Organization, emerged in Wuhan City …

Avoiding pitfalls in the pursuit of a COVID-19 vaccine

L Peeples - Proceedings of the national academy of …, 2020 - National Acad Sciences
The teams of researchers scrambling to develop a coronavirus disease 2019 (COVID-19)
vaccine clearly face some big challenges, both scientific and logistical. One of the most …