Cell penetrating peptides (CPPs) can deliver cell-impermeable therapeutic cargos into cells.
In particular, CPP-cargo conjugates tend to accumulate inside cells by endocytosis …

The hydrophilic nature of peptides and proteins renders them impermeable to cell
membranes. Thus, in order to successfully deliver peptide and protein-based therapeutics …

Abstract Cell-penetrating peptides (CPPs), often vividly termed as the “Trojan Horse”
peptides, have attracted considerable interest for the intracellular delivery of a wide range of …

During the last decade, small peptides (10 to 15 amino acids) derived from the HIV-1 Tat
protein and from the drosophila Antennapedia homeodomain have been used to internalize …

The penetration of biological membranes is a prime obstacle for the delivery of
pharmaceutical drugs. Cell-penetrating peptide (CPP) is an efficient vehicle that can deliver …

The use of CPPs (cell-penetrating peptides) as delivery vectors for bioactive molecules has
been an emerging field since 1994 when the first CPP, penetratin, was discovered. Since …

Cell-penetrating peptides (CPPs) are small molecules of major interest due to their ability to
efficiently transport cargos across cell membranes in a receptor-and energy-independent …

Efficient delivery of heterologous molecules for treatment of cells is a great challenge in
modern medicine and pharmacology. Cell-penetrating peptides (CPPs) may improve …

An important hurdle for the intracellular delivery of large cargo is the cellular membrane,
which protects the cell from exogenous substances. Cell-penetrating peptides (CPPs) can …

The selective infiltration of cell membranes and tissue barriers often blocks the entry of most
active molecules. This natural defense mechanism prevents the invasion of exogenous …