Cell penetrating peptides: classification, mechanisms, methods of study, and applications
A Gori, G Lodigiani, SG Colombarolli… - …, 2023 - Wiley Online Library
Cell‐penetrating peptides (CPPs) encompass a class of peptides that possess the
remarkable ability to cross cell membranes and deliver various types of cargoes, including …
remarkable ability to cross cell membranes and deliver various types of cargoes, including …
[HTML][HTML] Cell-penetrating peptides in diagnosis and treatment of human diseases: from preclinical research to clinical application
J Xie, Y Bi, H Zhang, S Dong, L Teng, RJ Lee… - Frontiers in …, 2020 - frontiersin.org
Cell-penetrating peptides (CPPs) are short peptides (fewer than 30 amino acids) that have
been predominantly used in basic and preclinical research during the last 30 years. Since …
been predominantly used in basic and preclinical research during the last 30 years. Since …
[HTML][HTML] Peptides as multifunctional players in cancer therapy
SMP Vadevoo, S Gurung, HS Lee… - … & Molecular Medicine, 2023 - nature.com
Peptides exhibit lower affinity and a shorter half-life in the body than antibodies. Conversely,
peptides demonstrate higher efficiency in tissue penetration and cell internalization than …
peptides demonstrate higher efficiency in tissue penetration and cell internalization than …
Peptides for cell-selective drug delivery
The ability to target specific cell types to achieve optimal distribution of therapeutic entities
into diseased tissues, while limiting possible adverse off-target effects, has long been a goal …
into diseased tissues, while limiting possible adverse off-target effects, has long been a goal …
Cell targeting peptides as smart ligands for targeting of therapeutic or diagnostic agents: a systematic review
A Mousavizadeh, A Jabbari, M Akrami… - Colloids and Surfaces B …, 2017 - Elsevier
Cell targeting peptides (CTP) are small peptides which have high affinity and specificity to a
cell or tissue targets. They are typically identified by using phage display and chemical …
cell or tissue targets. They are typically identified by using phage display and chemical …
On the biomedical promise of cell penetrating peptides: limits versus prospects
C Foerg, HP Merkle - Journal of pharmaceutical sciences, 2008 - Elsevier
The cell membrane poses a substantial hurdle to the use of pharmacologically active
biomacromolecules that are not per se actively translocated into cells. An appealing …
biomacromolecules that are not per se actively translocated into cells. An appealing …
Mechanism matters: a taxonomy of cell penetrating peptides
The permeability barrier imposed by cellular membranes limits the access of exogenous
compounds to the interior of cells. Researchers and patients alike would benefit from …
compounds to the interior of cells. Researchers and patients alike would benefit from …
Tumor‐homing peptide and its utility for advanced cancer medicine
Cell‐penetrating peptides, such as antibodies, have gained great attention as tools for the
development of specific delivery systems for payloads, which might be applied as non …
development of specific delivery systems for payloads, which might be applied as non …
Cell‐penetrating peptides: Nanocarrier for macromolecule delivery in living cells
A Chugh, F Eudes, YS Shim - IUBMB life, 2010 - Wiley Online Library
Novel classes and applications of cell‐penetrating peptides (CPPs) are being constantly
discovered since they were first identified 2 decades ago. These short cationic peptides …
discovered since they were first identified 2 decades ago. These short cationic peptides …
[HTML][HTML] Intracellular delivery of molecular cargo using cell-penetrating peptides and the combination strategies
H Li, TY Tsui, W Ma - International journal of molecular sciences, 2015 - mdpi.com
Cell-penetrating peptides (CPPs) can cross cellular membranes in a non-toxic fashion,
improving the intracellular delivery of various molecular cargos such as nanoparticles, small …
improving the intracellular delivery of various molecular cargos such as nanoparticles, small …