[HTML][HTML] Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway

KS Prabhu, AA Bhat, KS Siveen, S Kuttikrishnan… - Biomedicine & …, 2021 - Elsevier
Effective treatment of lung cancer remains a significant clinical challenge due to its multidrug
resistance and side effects of the current treatment options. The high mortality associated …

[HTML][HTML] Isolation and identification of phenolic compounds from Gynura divaricata leaves

C Wan, Y Yu, S Zhou, S Tian, S Cao - Pharmacognosy magazine, 2011 - ncbi.nlm.nih.gov
Background: Phenolic constituents were the principle bioactivity compounds exist in Gynura
divaricata, little phenolic compounds were reported from the plant previously. Materials and …

Regulation of the cell cycle and PI3K/Akt/mTOR signaling pathway by tanshinone I in human breast cancer cell lines Retraction in/10.3892/mmr. 2021.12080

L Wang, J Wu, J Lu, R Ma… - Molecular medicine …, 2015 - spandidos-publications.com
Breast cancer is the second leading cause of cancer‑related mortality in females worldwide.
Therefore, identifying alternative strategies to combat the disease mortality is important. The …

Sanguinarine inhibits epithelial–mesenchymal transition via targeting HIF-1α/TGF-β feed-forward loop in hepatocellular carcinoma

Q Su, M Fan, J Wang, A Ullah, MA Ghauri, B Dai… - Cell Death & …, 2019 - nature.com
Epithelial–mesenchymal transition (EMT) plays a crucial role in hepatocellular carcinoma
(HCC) progression. Hypoxia and excessive transforming growth factor-β (TGF-β) have been …

Danshen improves survival of patients with breast cancer and dihydroisotanshinone I induces ferroptosis and apoptosis of breast cancer cells

YS Lin, YC Shen, CY Wu, YY Tsai, YH Yang… - Frontiers in …, 2019 - frontiersin.org
Danshen (salvia miltiorrhiza Bunge) is widely used in traditional Chinese medicine.
However, it is definite clinical effort and mechanism on breast cancer is unclear. In our study …

[HTML][HTML] Tetrandrine and cancer–An overview on the molecular approach

N Bhagya, KR Chandrashekar - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Tetrandrine has been known in the treatment of tuberculosis, hyperglycemia, negative
ionotropic and chronotropic effects on myocardium, malaria, cancer and fever since years …

[HTML][HTML] Morin hydrate: A comprehensive review on novel natural dietary bioactive compound with versatile biological and pharmacological potential

SA Rajput, X Wang, HC Yan - Biomedicine & pharmacotherapy, 2021 - Elsevier
Flavonoids are natural plant-derived dietary bioactive compounds having a substantial
impact on human health. Morin hydrate is a bioflavonoid mainly obtained from fruits, stem …

Tanshinones: sources, pharmacokinetics and anti-cancer activities

Y Zhang, P Jiang, M Ye, SH Kim, C Jiang… - International journal of …, 2012 - mdpi.com
Tanshinones are a class of abietane diterpene compound isolated from Salvia miltiorrhiza
(Danshen or Tanshen in Chinese), a well-known herb in Traditional Chinese Medicine …

Gynostemma pentaphyllum an immortal herb with promising therapeutic potential: a comprehensive review on its phytochemistry and pharmacological perspective

A Ahmed, MA Saleem, F Saeed, M Afzaal… - … Journal of Food …, 2023 - Taylor & Francis
Gynostemma pentaphyllum belongs to the family Cucurbitaceae which is native to China
where it is also termed an immortal herb. It is an emerging herb gaining fame for its rich …

Hispidulin: A promising flavonoid with diverse anti-cancer properties

K Liu, F Zhao, J Yan, Z Xia, D Jiang, P Ma - Life Sciences, 2020 - Elsevier
In recent years, natural products have increasingly attracted more attention because of their
potential anticancer activity and low intrinsic toxicity. Hispidulin is a natural flavonoid with a …