Functional and clinical aspects of the B‐cell‐activating factor (BAFF): a narrative review

GA Lied, A Berstad - Scandinavian journal of immunology, 2011 - Wiley Online Library
B‐cell‐activating factor (BAFF) influences peripheral B‐cell survival, maturation and
immunoglobulin class‐switch recombination and has a range of potential clinical …

BAFF: B cell survival factor and emerging therapeutic target for autoimmune disorders

SL Kalled, C Ambrose, YM Hsu - Expert Opinion on Therapeutic …, 2003 - Taylor & Francis
The prevailing treatment strategies for autoimmune disorders employ global
immunosuppressants that have harmful side effects with long-term use. A new vision for …

New ELISA for B cell–activating factor

L Le Pottier, B Bendaoud, Y Renaudineau… - Clinical …, 2009 - academic.oup.com
Background: The B cell–activating factor of the TNF family (BAFF) is upregulated in
autoimmune diseases, but a number of conflicting results have cast doubts on the reliability …

BAFF: a local and systemic target in autoimmune diseases

I Moisini, A Davidson - Clinical & Experimental Immunology, 2009 - academic.oup.com
BAFF (B lymphocyte activating factor of the tumour necrosis factor family) is a vital
homeostatic cytokine for B cells that helps regulate both innate and adaptive immune …

The role of BAFF in immune function and implications for autoimmunity

SL Kalled - Immunological reviews, 2005 - Wiley Online Library
BAFF [B‐cell activating factor belonging to the tumor necrosis factor (TNF) family] is a ligand
that is required for peripheral B‐cell survival and homeostasis. In addition to mediating B …

Cracking the BAFF code

F Mackay, P Schneider - Nature reviews immunology, 2009 - nature.com
The tumour necrosis factor (TNF) family members B cell activating factor (BAFF) and APRIL
(a proliferation-inducing ligand) are crucial survival factors for peripheral B cells. An excess …

The late news on baff in autoimmune diseases

P Youinou, JO Pers - Autoimmunity reviews, 2010 - Elsevier
The B cell-activating factor of the tumor-necrosis factor family (BAFF) plays a dominant role
in the B cell homeostasis. By rescuing autoreactive B cells, excessive BAFF favors the …

The function of BAFF on T helper cells in autoimmunity

M Chen, X Lin, Y Liu, Q Li, Y Deng, Z Liu… - Cytokine & growth factor …, 2014 - Elsevier
B cell-activating factor belonging to the TNF family (BAFF) exerts its pathogenic role in
supporting the survival and proliferation of B cells, regulating class switch recombination as …

B cell activating factor, its role in autoimmunity, and targeting in autoimmune diseases.

M Krivosikova, T Dallos, W Maslinski… - Bratislavske lekarske …, 2009 - europepmc.org
B cell activation factor (BAFF), a recently identified member of the tumour necrosis factor
(TNF) family, is a key survival factor during B cell maturation and is essential for the …

[HTML][HTML] Function, occurrence and inhibition of different forms of BAFF

M Eslami, P Schneider - Current Opinion in Immunology, 2021 - Elsevier
B cell activating factor (BAFF or BLyS), an important cytokine for B cell survival and humoral
immune responses, is targeted in the clinic for the treatment of systemic lupus …