Transmitted HIV type 1 drug resistance among individuals with recent HIV infection in East and Southern Africa

MA Price, CL Wallis, S Lakhi, E Karita… - AIDS research and …, 2011 - liebertpub.com
To characterize WHO-defined transmitted HIV drug resistance mutation (TDRM) data from
recently HIV-infected African volunteers, we sequenced HIV (pol) and evaluated for TDRM …

HIV-1 antiretroviral drug resistance mutations in treatment naïve and experienced Panamanian subjects: impact on national use of EFV-based schemes

Y Mendoza, J Castillo Mewa, AA Martínez, Y Zaldívar… - PLoS …, 2016 - journals.plos.org
The use of antiretroviral therapy in HIV infected subjects prevents AIDS-related illness and
delayed occurrence of death. In Panama, rollout of ART started in 1999 and national …

Sensitive testing of plasma HIV-1 RNA and Sanger sequencing of cellular HIV-1 DNA for the detection of drug resistance prior to starting first-line antiretroviral therapy …

AM Geretti, T Conibear, A Hill… - Journal of …, 2014 - academic.oup.com
Objectives This study investigated strategies that may increase the yield of drug resistance
testing prior to starting antiretroviral therapy (ART), and whether transmitted and …

Trends in the molecular epidemiology and genetic mechanisms of transmitted human immunodeficiency virus type 1 drug resistance in a large US clinic population

SY Rhee, D Clutter, WJ Fessel, D Klein… - Clinical Infectious …, 2019 - academic.oup.com
Background There are few large studies of transmitted drug resistance (TDR) prevalence
and the drug resistance mutations (DRMs) responsible for TDR in the United States …

Reliability and clinical relevance of the HIV-1 drug resistance test in patients with low viremia levels

MM Santoro, L Fabeni, D Armenia… - Clinical infectious …, 2014 - academic.oup.com
Background. We evaluated reliability and clinical usefulness of genotypic resistance testing
(GRT) in patients for whom combination antiretroviral therapy (cART) was unsuccessful with …

Emergence of acquired HIV-1 drug resistance almost stopped in Switzerland: a 15-year prospective cohort analysis

AU Scherrer, V Von Wyl, WL Yang… - Clinical infectious …, 2016 - academic.oup.com
Background. Drug resistance is a major barrier to successful antiretroviral treatment (ART).
Therefore, it is important to monitor time trends at a population level. Methods. We included …

Long-term trends of HIV type 1 drug resistance prevalence among antiretroviral treatment–experienced patients in Switzerland

V von Wyl, S Yerly, J Böni, P Bürgisser… - Clinical Infectious …, 2009 - academic.oup.com
Background. Accurate quantification of the prevalence of human immunodeficiency virus
type 1 (HIV-1) drug resistance in patients who are receiving antiretroviral therapy (ART) is …

Characterizing the emergence and persistence of drug resistant mutations in HIV-1 subtype C infections using 454 ultra deep pyrosequencing

V Bansode, GP McCormack, AC Crampin… - BMC infectious …, 2013 - Springer
Background The role of HIV-1 RNA in the emergence of resistance to antiretroviral therapies
(ARTs) is well documented while less is known about the role of historical viruses stored in …

Prevalence of transmitted drug resistance associated mutations and HIV-1 subtypes in new HIV-1 diagnoses, US–2006

WH Wheeler, RA Ziebell, H Zabina, D Pieniazek… - Aids, 2010 - journals.lww.com
Objective: To determine the distribution of HIV-1 subtypes and the prevalence of transmitted
drug resistance-associated mutations (TDRM) among persons newly diagnosed with HIV-1 …

National sentinel surveillance of transmitted drug resistance in antiretroviral-naive chronically HIV-infected patients in France over a decade: 2001–2011

D Descamps, L Assoumou, ML Chaix… - Journal of …, 2013 - academic.oup.com
Objectives As recommended by the French ANRS programme for the surveillance of HIV-1
resistance, we estimated the prevalence of transmitted drug resistance-associated mutations …