Discovery of new antibacterials with novel mechanisms is important to counteract the
ingenious resistance mechanisms of bacteria. In this connection, omics-guided drug …

Aeromonas hydrophila is a widespread opportunistic pathogen of aquatic fishes in
freshwater habitats. The current emergence of antimicrobial-resistant A. hydrophila has …

Drug efflux pumps confer resistance upon bacteria to a wide range of antibiotics from
various classes. The expression of efflux pumps are also implicated in virulence and biofilm …

Microbes have shown a remarkable ability in evading the killing actions of antimicrobial
agents, such that treatment of bacterial infections represents once more an urgent global …

The problem of antibiotic resistance is a global critical public health concern. In light of the
threat of returning to the pre-antibiotic era, new alternative approaches are required such as …

Serratia marcescens (S. marcescens) is an environmental bacterium that causes infections
with high morbidity and mortality. Notably, infections caused by multidrug-resistant S …

We investigated the responses and mechanisms of action of methicillin-resistant
Staphylococcus aureus (MRSA) metabolism when exposed under sublethal concentrations …

Antibacterial agents have saved many lives and helped the growth of modern medicine over
the past half century. The emergence of drug resistance, jeopardizing the effectiveness of …

The research on pharmacology usually focuses on the structure-activity relationships of
drugs, such as antibiotics, to enhance their activity, but often ignores their optical properties …

Natural product antibiotics have played an essential role in the treatment of bacterial
infection in addition to serving as useful tools to explore the intricate biology of bacteria. Our …