Systematic comparison of hospital-wide Standard and Model-based therapeutic drug monitoring of vancomycin in adults

H Gastmans, E Dreesen, SG Wicha, N Dia… - Pharmaceutics, 2022 - mdpi.com
We aimed to evaluate the predictive performance and predicted doses of a single-model
approach or several multi-model approaches compared with the standard therapeutic drug …

Clinical practice guidelines for therapeutic drug monitoring of vancomycin in the framework of model-informed precision dosing: a consensus review by the Japanese …

K Matsumoto, K Oda, K Shoji, Y Hanai, Y Takahashi… - Pharmaceutics, 2022 - mdpi.com
Background: To promote model-informed precision dosing (MIPD) for vancomycin (VCM),
we developed statements for therapeutic drug monitoring (TDM). Methods: Ten clinical …

Accuracy of 4 Free Online Dosing Calculators in Predicting the Vancomycin Area Under the Concentration-Time Curve Calculated Using a 2-Point Pharmacokinetic …

SN Belz, RW Seabury, JM Steele… - Annals of …, 2023 - journals.sagepub.com
Background: Free online adaptive vancomycin dosing calculators are available to estimate
area under the concentration-time curve (AUC), but the accuracy of predicting vancomycin …

Evaluation of a Bayesian method for predicting vancomycin dosing

ME Burton, DL Gentle, MR Vasko - 1989 - journals.sagepub.com
The purpose of this study is to evaluate the performance of a vancomycin dosing program in
predicting dosages necessary to achieve desired serum vancomycin concentrations in a …

[HTML][HTML] External validation of vancomycin population pharmacokinetic models in ten cohorts of infected Chinese patients

Y Zhou, E Long, T Shi, Z Wang, J Zhao, H Liu… - Journal of Global …, 2022 - Elsevier
Objectives Appropriate dosage of vancomycin is critical for safety and efficacy in treating
infectious diseases. Various population pharmacokinetic (PPK) models have been …

Dose optimization and target attainment of vancomycin in children

A Cafaro, M Stella, A Mesini, E Castagnola… - Clinical …, 2024 - Elsevier
Vancomycin is a glycopeptide antibiotic that has been adopted in clinical practice to treat
gram-positive infections for more than 70 years. Despite vancomycin's long history of …

Determination of vancomycin exposure target and individualized dosing recommendations for critically ill patients undergoing continuous renal replacement therapy

C Wang, J Chen, B Yang, S Li, Y Zhang… - … : The Journal of …, 2023 - Wiley Online Library
Abstract Study Objective Few studies have been conducted to quantify the exposure target
of vancomycin in intensive care unit (ICU) patients undergoing continuous renal …

[HTML][HTML] Towards precision dosing of vancomycin: a systematic evaluation of pharmacometric models for Bayesian forecasting

A Broeker, M Nardecchia, KP Klinker… - Clinical Microbiology …, 2019 - Elsevier
Objectives Vancomycin is a vital treatment option for patients suffering from critical
infections, and therapeutic drug monitoring is recommended. Bayesian forecasting is …

Vancomycin dosing, monitoring and toxicity: Critical review of the clinical practice

W Zamoner, IRS Prado, AL Balbi… - Clinical and …, 2019 - Wiley Online Library
Vancomycin is an antibiotic used in the treatment of infections caused by multidrug‐resistant
Gram‐positive bacteria, especially methicillin‐resistant Staphylococcus aureus. In the last …

Vancomycin area under the concentration-time curve estimation using bayesian modeling versus first-order pharmacokinetic equations: a quasi-experimental study

YS Alsowaida, DW Kubiak, B Dionne, MP Kovacevic… - Antibiotics, 2022 - mdpi.com
Aim: To evaluate the efficiency of Bayesian modeling software and first-order
pharmacokinetic (PK) equations to calculate vancomycin area under the concentration-time …