Chemerin was isolated as the natural ligand of the G protein-coupled receptor ChemR23.
Chemerin acts as a chemotactic factor for leukocyte populations expressing ChemR23 …

Chemerin is a proinflammatory plasma protein that binds to the GPCR ChemR23/CMKLR1
on macrophages and plasmacytoid dendritic cells, and promotes chemotaxis. An orphan …

Dendritic cells (DCs) and macrophages are professional antigen-presenting cells (APCs)
that play key roles in both innate and adaptive immunity. ChemR23 is an orphan G protein …

Obesity and type 2 diabetes have reached epidemic levels and account for a substantial
portion of the annual health expenditures of developed nations. While there is an …

Chemerin is a secreted protein with a complex but well-established role in immune function.
Parallel lines of investigation also support the notion that chemerin is a novel adipokine that …

Chemerin is the ligand of the ChemR23 receptor and a chemoattractant factor for human
immature dendritic cells (DCs), macrophages, and NK cells. In this study, we characterized …

Overweight and adiposity are risk factors for several diseases, like type 2 diabetes and
cancer. White adipose tissue is a major source for adipokines, comprising a diverse group of …

Chemerin is an adipokine with important regulatory roles in adipogenesis. In humans, serum
total chemerin (ie prochemerin plus chemerin) levels are positively associated with body …

Chemerin, a recognized chemoattractant, is expressed in adipose tissue and plays a role in
adipocytes differentiation and metabolism. Gender-and adipose tissue-specific differences …

To explore a novel adipokine, we screened adipocyte differentiation-related gene and found
that TIG2/chemerin was strongly induced during the adipocyte differentiation. Chemerin was …