The vascular endothelium is a monolayer of cells between the vessel lumen and the
vascular smooth muscle cells. Nitric oxide (NO) is a soluble gas continuously synthesized …

Nitric oxide is a soluble gas continuously synthesized by the endothelium. This substance
has a wide range of biological properties that maintain vascular homeostasis, including …

The endothelium is a single cell layer that lines all blood vessels. This tissue produces an
impressive array of paracrine factors that maintain vascular homeostasis. One of these …

Atherosclerosis is a chronic inflammatory process in the intima of conduit arteries, which
disturbs the endothelium‐dependent regulation of the vascular tone by the labile liposoluble …

Nitric oxide (NO) is a molecule that has gained recognition as a crucial modulator of
vascular disease. NO has a number of intracellular effects that lead to vasorelaxation …

Nitric oxide (NO) is a pivotal signaling messenger in the cardiovascular system. NO
participates in regulatory functions including control of hemostasis, fibrinolysis, platelet and …

Since its discovery, endothelium-derived nitric oxide (NO) has become one of the most
intensely investigated molecules in the field of cardiovascular physiology. Although initial …

Nitric oxide (NO) is a relative newcomer to pharmacology, as the paper which initiated the
field was published only 25 years ago. Nevertheless its impact is such that to date more than …

Nitric oxide (NO) is a structurally simple, highly versatile molecule that was originally
discovered over 30 years ago as an endothelium-derived relaxing factor. In addition to its …

Nitric oxide produced by three different isoforms of nitric oxide synthase (NOS) widely
expressed in virtually all vascular cell types is mostly produced by the endothelial isoform …