Growth and differentiation factor-5 (GDF-5) stimulates osteogenic differentiation and increases vascular endothelial growth factor (VEGF) levels in fat-derived stromal …
Q Zeng, X Li, G Beck, G Balian, FH Shen - Bone, 2007 - Elsevier
Fat-derived adult mesenchymal stem cells can differentiate into different phenotypes
reflecting their potential to regenerate various skeletal tissues. These properties together …
reflecting their potential to regenerate various skeletal tissues. These properties together …
Recombinant growth/differentiation factor-5 stimulates osteogenic differentiation of fat-derived stromal cells in vitro
Q Zeng, X Li, L Choi, G Beck, G Balian… - Connective tissue …, 2006 - Taylor & Francis
Fat-derived stromal cells can differentiate into various skeletal tissues. Currently the
mechanism that determines whether stromal cells differentiate into osteoblasts is unclear …
mechanism that determines whether stromal cells differentiate into osteoblasts is unclear …
Growth/differentiation factor-5 induces angiogenesisin vivo
H Yamashita, A Shimizu, M Kato, H Nishitoh… - Experimental cell …, 1997 - Elsevier
Bone morphogenetic proteins (BMPs) are multifunctional cytokines, which induce bone and
cartilage formation and exert various other effects on many tissues. Since angiogenesis is …
cartilage formation and exert various other effects on many tissues. Since angiogenesis is …
Inductive activity of recombinant human growth and differentiation factor-5
RC Spiro, LS Liu, MA Heidaran, AY Thompson, CK Ng… - 2000 - portlandpress.com
Growth and differentiation factor-5 (GDF-5) is a divergent member of the transforming growth
factor-β/bone morphogenetic protein (BMP) superfamily that is required for proper skeletal …
factor-β/bone morphogenetic protein (BMP) superfamily that is required for proper skeletal …
Human adipose-derived stromal cells respond to and elaborate bone morphogenetic protein-2 during in vitro osteogenic differentiation
NJ Panetta, DM Gupta, JK Lee, DC Wan… - Plastic and …, 2010 - journals.lww.com
Background: Interest in the potential application of adipose-derived stromal cells in cell-
mediated tissue engineering of bone and other mesenchymal-derived tissues is growing …
mediated tissue engineering of bone and other mesenchymal-derived tissues is growing …
FGF‐2 abolishes the chondrogenic effect of combined BMP‐6 and TGF‐β in human adipose derived stem cells
F Hildner, A Peterbauer, S Wolbank… - … research Part A, 2010 - Wiley Online Library
In this study, we investigated the influence of transforming growth factor beta 3 (TGF‐β3),
bone morphogenetic protein 6 (BMP‐6) and basic fibroblast growth factor (FGF‐2) on …
bone morphogenetic protein 6 (BMP‐6) and basic fibroblast growth factor (FGF‐2) on …
BMP7 promotes adipogenic but not osteo‐/chondrogenic differentiation of adult human bone marrow‐derived stem cells in high‐density micro‐mass culture
K Neumann, M Endres, J Ringe, B Flath… - Journal of cellular …, 2007 - Wiley Online Library
The objective of our study was to elucidate the potential of bone morphogenetic protein-7
(BMP7) to initiate distinct mesenchymal lineage development of human adult mesenchymal …
(BMP7) to initiate distinct mesenchymal lineage development of human adult mesenchymal …
Osteogenesis versus chondrogenesis by BMP-2 and BMP-7 in adipose stem cells
M Knippenberg, MN Helder, BZ Doulabi… - Biochemical and …, 2006 - Elsevier
Bone morphogenetic proteins (BMPs) initiate, promote, and maintain chondrogenesis and
osteogenesis. We hypothesize that BMP-2 induces an osteogenic, and BMP-7 a …
osteogenesis. We hypothesize that BMP-2 induces an osteogenic, and BMP-7 a …
Mitogenic and chondrogenic effects of fibroblast growth factor-2 in adipose-derived mesenchymal cells
M Chiou, Y Xu, MT Longaker - Biochemical and biophysical research …, 2006 - Elsevier
Adipose-derived mesenchymal cells (AMCs) have demonstrated a great capacity for
differentiating into bone, cartilage, and fat. Studies using bone marrow-derived …
differentiating into bone, cartilage, and fat. Studies using bone marrow-derived …
Growth differentiation factor-5 enhances in vitro mesenchymal stromal cell chondrogenesis and hypertrophy
CM Coleman, EE Vaughan, DC Browe… - Stem cells and …, 2013 - liebertpub.com
The regenerative potential for adult bone marrow-derived mesenchymal stromal cells
(MSCs) has been extensively investigated in the setting of arthritic disease and focal …
(MSCs) has been extensively investigated in the setting of arthritic disease and focal …