Molecular determinants of clinical outcomes in a real-world diffuse large B-cell lymphoma population
W Alduaij, B Collinge, S Ben-Neriah… - Blood, The Journal …, 2023 - ashpublications.org
Molecular heterogeneity of diffuse large B-cell lymphoma (DLBCL) underlies the variable
outcomes achieved with immunochemotherapy. However, outcomes of gene expression …
outcomes achieved with immunochemotherapy. However, outcomes of gene expression …
Molecular high-grade B-cell lymphoma: defining a poor-risk group that requires different approaches to therapy
Purpose Biologic heterogeneity is a feature of diffuse large B-cell lymphoma (DLBCL), and
the existence of a subgroup with poor prognosis and phenotypic proximity to Burkitt …
the existence of a subgroup with poor prognosis and phenotypic proximity to Burkitt …
MYC/BCL2 protein coexpression contributes to the inferior survival of activated B-cell subtype of diffuse large B-cell lymphoma and demonstrates high-risk gene …
Diffuse large B-cell lymphoma (DLBCL) is stratified into prognostically favorable germinal
center B-cell (GCB)–like and unfavorable activated B-cell (ABC)–like subtypes based on …
center B-cell (GCB)–like and unfavorable activated B-cell (ABC)–like subtypes based on …
Double-hit gene expression signature defines a distinct subgroup of germinal center B-cell-like diffuse large B-cell lymphoma
D Ennishi, A Jiang, M Boyle, B Collinge… - Journal of Clinical …, 2019 - ascopubs.org
Purpose High-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements
(HGBL-DH/TH) has a poor outcome after standard chemoimmunotherapy. We sought to …
(HGBL-DH/TH) has a poor outcome after standard chemoimmunotherapy. We sought to …
Comprehensive gene expression profiling and immunohistochemical studies support application of immunophenotypic algorithm for molecular subtype classification …
Gene expression profiling (GEP) has stratified diffuse large B-cell lymphoma (DLBCL) into
molecular subgroups that correspond to different stages of lymphocyte development …
molecular subgroups that correspond to different stages of lymphocyte development …
The double-hit signature identifies double-hit diffuse large B-cell lymphoma with genetic events cryptic to FISH
LK Hilton, J Tang, S Ben-Neriah… - Blood, The Journal …, 2019 - ashpublications.org
High-grade B-cell lymphomas with MYC and BCL2 and/or BCL6 rearrangements (HGBL-
DH/THs) include a group of diffuse large B-cell lymphomas (DLBCLs) with inferior outcomes …
DH/THs) include a group of diffuse large B-cell lymphomas (DLBCLs) with inferior outcomes …
Genetic profiling of MYC and BCL2 in diffuse large B-cell lymphoma determines cell-of-origin–specific clinical impact
D Ennishi, A Mottok, S Ben-Neriah… - Blood, The Journal …, 2017 - ashpublications.org
The clinical significance of MYC and BCL2 genetic alterations in diffuse large B-cell
lymphoma (DLBCL), apart from translocations, has not been comprehensively investigated …
lymphoma (DLBCL), apart from translocations, has not been comprehensively investigated …
Are we ready to stratify treatment for diffuse large B-cell lymphoma using molecular hallmarks?
S Barton, EA Hawkes, A Wotherspoon… - The …, 2012 - academic.oup.com
abstract Learning Objectives: After completing this course, the reader will be able to:
Describe the oncogenic drivers in DLBCL, especially those that have recently been …
Describe the oncogenic drivers in DLBCL, especially those that have recently been …
Cell-of-origin in diffuse large B-cell lymphoma: are the assays ready for the clinic?
DW Scott - American Society of Clinical Oncology Educational …, 2015 - ascopubs.org
Diffuse large B-cell lymphoma (DLBCL) is the most common lymphoma worldwide and
consists of a heterogeneous group of cancers classified together on the basis of shared …
consists of a heterogeneous group of cancers classified together on the basis of shared …
[HTML][HTML] Proposal and validation of a method to classify genetic subtypes of diffuse large B cell lymphoma
L Pedrosa, I Fernández-Miranda, D Pérez-Callejo… - Scientific reports, 2021 - nature.com
Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease whose prognosis is
associated with clinical features, cell-of-origin and genetic aberrations. Recent integrative …
associated with clinical features, cell-of-origin and genetic aberrations. Recent integrative …