[HTML][HTML] Stratifying diffuse large B-cell lymphoma patients treated with chemoimmunotherapy: GCB/non-GCB by immunohistochemistry is still a robust and feasible …

A Batlle-López, SG De Villambrosía, M Francisco… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Diffuse large B cell lymphoma (DLBCL) is a heterogeneous group of aggressive lymphomas
that can be classified into three molecular subtypes by gene expression profiling (GEP) …

Molecular profiling in diffuse large B‐cell lymphoma: why so many types of subtypes?

RD Morin, SE Arthur, DJ Hodson - British Journal of …, 2022 - Wiley Online Library
The term diffuse large B‐cell lymphoma (DLBCL) includes a heterogeneous collection of
biologically distinct tumours. This heterogeneity currently presents a barrier to the successful …

Immunoblastic morphology but not the immunohistochemical GCB/nonGCB classifier predicts outcome in diffuse large B-cell lymphoma in the RICOVER-60 trial of the …

G Ott, M Ziepert, W Klapper, H Horn… - Blood, The Journal …, 2010 - ashpublications.org
The survival of diffuse large B-cell lymphoma patients varies considerably, reflecting the
molecular diversity of tumors. In view of the controversy whether cytologic features …

ABC, GCB, and double-hit diffuse large B-cell lymphoma: does subtype make a difference in therapy selection?

GS Nowakowski, MS Czuczman - American Society of Clinical …, 2015 - ascopubs.org
Personalized therapy for the treatment of patients with cancer is rapidly approaching and is
an achievable goal in the near future. A substantial number of novel targets have been …

Evaluating cell-of-origin subtype methods for predicting diffuse large B-cell lymphoma survival: a meta-analysis of gene expression profiling and …

JA Read, JL Koff, LJ Nastoupil, JN Williams… - … Myeloma and Leukemia, 2014 - Elsevier
Background Patients with DLBCL exhibit widely divergent outcomes despite harboring
histologically identical tumors. Currently, GEP and IHC algorithms assign patients to 1 of 2 …

Whole exome sequencing of relapsed/refractory patients expands the repertoire of somatic mutations in diffuse large B‐cell lymphoma

S Mareschal, S Dubois, PJ Viailly… - Genes …, 2016 - Wiley Online Library
Despite the many efforts already spent to enumerate somatic mutations in diffuse large B‐
cell lymphoma (DLBCL), previous whole‐genome and whole‐exome studies conducted on …

Diffuse large B-cell lymphoma: optimizing outcome in the context of clinical and biologic heterogeneity

LH Sehn, RD Gascoyne - Blood, The Journal of the American …, 2015 - ashpublications.org
Although the majority of patients with diffuse large B-cell lymphoma (DLBCL) can be cured
with standard rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R …

A probabilistic classification tool for genetic subtypes of diffuse large B cell lymphoma with therapeutic implications

GW Wright, JD Phelan, ZA Coulibaly, S Roulland… - Cancer cell, 2020 - cell.com
The development of precision medicine approaches for diffuse large B cell lymphoma
(DLBCL) is confounded by its pronounced genetic, phenotypic, and clinical heterogeneity …

Microarray‐based classification of diffuse large B‐cell lymphoma

CB Poulsen, R Borup, FC Nielsen… - European journal of …, 2005 - Wiley Online Library
Objective: Hierarchical clusterings of diffuse large B‐cell lymphoma (DLBCL) based on gene
expression signatures have previously been used to classify DLBCL into Germinal Center B …

Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response

S Monti, KJ Savage, JL Kutok, F Feuerhake, P Kurtin… - Blood, 2005 - ashpublications.org
Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease with recognized
variability in clinical outcome, genetic features, and cells of origin. To date, transcriptional …