Highlights•Microfluidic biomaterials enable immediate perfusion of an engineered
tissue.•Mechanical stresses govern the long-term vascular stability in these materials.• …

Over the last decade, highly innovative micro-fabrication techniques have been developed
that are set to revolutionise the biomedical industry. Fabrication processes, such as …

Highlights•A review on current microfluidic in vitro models for vascular tissue
engineering.•Vascular tissue engineering is essential to the success of regenerative …

Microfluidic systems have emerged as a new class of perfusable in vitro culture models that
have helped advance and refine our understanding of microvascular function. Cutting‐edge …

Engineering functional vascular networks in vitro is critical for tissue engineering and a
variety of applications. There is still a general lack of straightforward approaches for …

Microfluidics is invaluable for studying microvasculature, development of organ-on-chip
models and engineering microtissues. Microfluidic design can cleverly control geometry …

Highlights•Summary of key characteristics of microfluidics and hydrogels.•Current strategies
for integration between microfluidics and hydrogels.•Use of these new devices in order to …

In the past decade, significant advances have been made in the design and optimization of
novel biomaterials and microfabrication techniques to generate vascularized tissues. Novel …

Neovascularization, the formation of new blood vessels, has received much research
attention due to its implications for physiological processes and diseases. Most studies …

A major challenge in tissue engineering is the lack of proper vascularization of the fabricated
tissue constructs. Microscale technologies, especially microfluidic systems, provide new …